Overlooked and valuable facts to know in the NRF2/KEAP1 field

Aleksandra Kopacz; Ana I. Rojo; Chinmai Patibandla; Diego Lastra-Martínez; Aleksandra Piechota-Polanczyk; Damian Kloska; Alicja Jozkowicz; Calum Sutherland; Antonio Cuadrado; Anna Grochot-Przeczek

doi:10.1016/j.freeradbiomed.2022.08.044

Overlooked and valuable facts to know in the NRF2/KEAP1 field

Aleksandra Kopacz, Ana I. Rojo, Chinmai Patibandla, Diego Lastra-Martínez, Aleksandra Piechota-Polanczyk, Damian Kloska, Alicja Jozkowicz, Calum Sutherland, Antonio Cuadrado, Anna Grochot-Przeczek (Lead / Corresponding author)

Research output: Contribution to journal › Review article › peer-review

23 Citations (Scopus)

206 Downloads (Pure)

Original language	English
Pages (from-to)	37-49
Number of pages	13
Journal	Free Radical Biology and Medicine
Volume	192
Early online date	12 Sept 2022
DOIs	https://doi.org/10.1016/j.freeradbiomed.2022.08.044
Publication status	Published - 1 Nov 2022

Keywords

KEAP1
NRF2
antibodies
knockout mice
molecular weight
oxidative stress

ASJC Scopus subject areas

Biochemistry
Physiology (medical)

Access to Document

10.1016/j.freeradbiomed.2022.08.044Licence: CC BY-NC-ND

Final published versionFinal published version, 7.89 MBLicence: CC BY-NC-ND

Cite this

@article{d131aa1d4435421f95b603a80e66ef4c,

title = "Overlooked and valuable facts to know in the NRF2/KEAP1 field",

keywords = "KEAP1, NRF2, antibodies, knockout mice, molecular weight, oxidative stress",

author = "Aleksandra Kopacz and Rojo, {Ana I.} and Chinmai Patibandla and Diego Lastra-Mart{\'i}nez and Aleksandra Piechota-Polanczyk and Damian Kloska and Alicja Jozkowicz and Calum Sutherland and Antonio Cuadrado and Anna Grochot-Przeczek",

note = "Funding Information: This article is based upon work from COST Action CA2012, supported by COST (European Cooperation in Science and Technology) (www.cost.eu) (https://benbedphar.org/about-benbedphar/). This research was funded by the Spanish Ministry of Economy and Competitiveness (MINECO) (grants PID2019-110061RB-I00, and PDC2021-121421-I00) and The Autonomous Community of Madrid (grant B2017/BMD-3827). FLM enjoyed FPI contract of MINECO (FPI-2017). The National Science Centre supported this work with grants Sonata Bis No. 2016/22/E/NZ3/00405 (AGP), Opus No. 2021/43/B/NZ4/02130 (AGP), and Sonata No. 2018/31/D/NZ4/00077 (APP). AK is supported by L'Oreal for Women in Science and START Scholarship from Foundation for Polish Science. CP and CS are supported by Diabetes UK award 20/0006178.",

year = "2022",

month = nov,

day = "1",

doi = "10.1016/j.freeradbiomed.2022.08.044",

language = "English",

volume = "192",

pages = "37--49",

journal = "Free Radical Biology and Medicine",

issn = "0891-5849",

publisher = "Elsevier",

}

TY - JOUR

T1 - Overlooked and valuable facts to know in the NRF2/KEAP1 field

AU - Kopacz, Aleksandra

AU - Rojo, Ana I.

AU - Patibandla, Chinmai

AU - Lastra-Martínez, Diego

AU - Piechota-Polanczyk, Aleksandra

AU - Kloska, Damian

AU - Jozkowicz, Alicja

AU - Sutherland, Calum

AU - Cuadrado, Antonio

AU - Grochot-Przeczek, Anna

N1 - Funding Information: This article is based upon work from COST Action CA2012, supported by COST (European Cooperation in Science and Technology) (www.cost.eu) (https://benbedphar.org/about-benbedphar/). This research was funded by the Spanish Ministry of Economy and Competitiveness (MINECO) (grants PID2019-110061RB-I00, and PDC2021-121421-I00) and The Autonomous Community of Madrid (grant B2017/BMD-3827). FLM enjoyed FPI contract of MINECO (FPI-2017). The National Science Centre supported this work with grants Sonata Bis No. 2016/22/E/NZ3/00405 (AGP), Opus No. 2021/43/B/NZ4/02130 (AGP), and Sonata No. 2018/31/D/NZ4/00077 (APP). AK is supported by L'Oreal for Women in Science and START Scholarship from Foundation for Polish Science. CP and CS are supported by Diabetes UK award 20/0006178.

PY - 2022/11/1

Y1 - 2022/11/1

KW - KEAP1

KW - NRF2

KW - antibodies

KW - knockout mice

KW - molecular weight

KW - oxidative stress

UR - http://www.scopus.com/inward/record.url?scp=85138217303&partnerID=8YFLogxK

U2 - 10.1016/j.freeradbiomed.2022.08.044

DO - 10.1016/j.freeradbiomed.2022.08.044

M3 - Review article

C2 - 36100148

SN - 0891-5849

VL - 192

SP - 37

EP - 49

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

ER -

Overlooked and valuable facts to know in the NRF2/KEAP1 field

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Role of the GSK-3NRF2 Axis In Beta Cell Decline In Type 2 Diabetes

Aref#d: 20985. Quantitative Analysis of Key Protein Phosphorylation Events Pathway Biomarkers of Metabolic Disease in Human Cells

Cite this

Overlooked and valuable facts to know in the NRF2/KEAP1 field

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Projects

Role of the GSK-3NRF2 Axis In Beta Cell Decline In Type 2 Diabetes

Aref#d: 20985. Quantitative Analysis of Key Protein Phosphorylation Events Pathway Biomarkers of Metabolic Disease in Human Cells

Cite this