Twenty-five DSM-III-diagnosed schizophrenics and 37 normal and age-matched controls were examined using an oddball paradigm for the generation of P300 and smooth eye-pursuit tasks. Results were compared between groups and related to clinical characteristics, including a family history of psychiatric illness. Group differences were found for P300 amplitudes, latencies and eye-tracking. A family history of psychiatric illness was associated with normal eye-tracking in patients. Small P300 amplitudes alone and in combination with long P300 latencies were associated with a family history in controls.
|Number of pages||6|
|Journal||Acta Psychiatrica Scandinavica|
|Publication status||Published - 1990|
Ebmeier, E. K. P., Potter, D. D., Cochrane, R. H. B., Mackenzie, A. R., McAllister, H., Besson, J. A. O., & Salzen, E. A. (1990). P3OO and smooth eye pursuit: concordance of abnormalities and relation to clinical features in DSM-III schizophrenia. Acta Psychiatrica Scandinavica, 82(4), 283-288. https://doi.org/10.1111/j.1600-0447.1990.tb01385.x