p53 isoforms change p53 paradigm

J C Bourdon

doi:10.4161/23723548.2014.969136

p53 isoforms change p53 paradigm

J C Bourdon

Research output: Contribution to journal › Article › peer-review

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177 Downloads (Pure)

Abstract

Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cellular response to treatment.

Original language	English
Pages (from-to)	e969136
Journal	Molecular and Cellular Oncology
Volume	1
Issue number	4
Early online date	31 Dec 2014
DOIs	https://doi.org/10.4161/23723548.2014.969136
Publication status	Published - 2014

Keywords

Journal Article

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4161/23723548.2014.969136Licence: CC BY-NC

Final published versionFinal published version, 1.53 MBLicence: CC BY-NC

Cite this

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AB - Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cellular response to treatment.

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p53 isoforms change p53 paradigm

Abstract

Keywords

UN SDGs

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