p53 levels govern the choice between senescence and quiescence

David W. Meek

    Research output: Contribution to journalEditorialpeer-review

    Abstract

    The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling.

    Original languageEnglish
    Pages (from-to)637-638
    Number of pages2
    JournalAging-US
    Volume2
    Issue number10
    Publication statusPublished - Oct 2010

    Keywords

    • CELLULAR SENESCENCE
    • PATHWAY

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