Abstract
The mechanism(s) by which p53 chooses between outcomes of senescence or quiescence has remained elusive. A paper published in the recent issue of Cell Cycle indicates that this decision may be determined by p53 levels and their ability to selectively down-regulate mTOR signaling.
Original language | English |
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Pages (from-to) | 637-638 |
Number of pages | 2 |
Journal | Aging |
Volume | 2 |
Issue number | 10 |
Publication status | Published - Oct 2010 |
Keywords
- CELLULAR SENESCENCE
- PATHWAY