Palisaded neutrophilic granulomatous dermatitis associated with systemic lupus erythematosus presenting with the burning rope sign

Abha Gulati, David Paige, Magdi Yaqoob, Charlotte M. Proby, Rino Cerio, Catherine A. Harwood

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    21 Citations (Scopus)

    Abstract

    Palisaded neutrophilic granulomatous dermatitis is a rare but increasingly recognized cutaneous manifestation of connective tissue disorders. it is reported most commonly with rheumatoid arthritis but also occasionally in association with systemic lupus erythematosus, inflammatory bowel disease, lymphoproliferative disorders, and systemic vasculitides. The clinicopathological presentation is highly variable, which has led to Suggestions that it encompasses a number of distinct diseases. Most previous cases have reported only a single clinical and histologic manifestation of the condition within an individual. Here, we present a case of systemic lupus erythematosus-associated palisaded neutrophilic granulomatous dermatitis in which a striking evolution of both clinical and histologic features was observed during the Course of 7 years, providing compelling evidence for the proposal that palisaded neutrophilic granulomatous dermatitis represents a disease spectrum rather than separate disease entities. (J Am Acad Dermatol 2009;61:711-4.)

    Original languageEnglish
    Pages (from-to)711-714
    Number of pages4
    JournalJournal of the American Academy of Dermatology
    Volume61
    Issue number4
    DOIs
    Publication statusPublished - Oct 2009

    Keywords

    • palisaded neutrophilic granulomatous dermatitis
    • SLE
    • RHEUMATOID-ARTHRITIS
    • SPECTRUM

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