Paracetamol toxicity: epidemiology, prevention and costs to the health-care system

C. L. Sheen, J. F. Dillon, D. N. Bateman, K. J. Simpson, T. M. Macdonald

    Research output: Contribution to journalArticle

    91 Citations (Scopus)

    Abstract

    Paracetamol has been used as an analgesic and antipyretic for many years, with toxicity first noted in the 1960s. Since then the incidence of poisoning has increased, and paracetamol is now the most common drug in self-poisoning, with a high rate of morbidity and mortality. The use, abuse and ways of reducing paracetamol toxicity are reviewed, but in view of the potential for harm, serious consideration should be given to changing the legal status of paracetamol, possibly to a prescription-only medicine.
    Original languageEnglish
    Pages (from-to)609-619
    Number of pages11
    JournalQJM : an International Journal of Medicine
    Volume95
    Issue number9
    DOIs
    Publication statusPublished - 2002

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