Paracetamol toxicity:: epidemiology, prevention and costs to the health-care system

C. L. Sheen; J. F. Dillon; D. N. Bateman; K. J. Simpson; T. M. Macdonald

doi:10.1093/qjmed/95.9.609

Paracetamol toxicity: epidemiology, prevention and costs to the health-care system

C. L. Sheen, J. F. Dillon, D. N. Bateman, K. J. Simpson, T. M. Macdonald

Research output: Contribution to journal › Article › peer-review

109 Citations (Scopus)

Abstract

Paracetamol has been used as an analgesic and antipyretic for many years, with toxicity first noted in the 1960s. Since then the incidence of poisoning has increased, and paracetamol is now the most common drug in self-poisoning, with a high rate of morbidity and mortality. The use, abuse and ways of reducing paracetamol toxicity are reviewed, but in view of the potential for harm, serious consideration should be given to changing the legal status of paracetamol, possibly to a prescription-only medicine.

Original language	English
Pages (from-to)	609-619
Number of pages	11
Journal	QJM : an International Journal of Medicine
Volume	95
Issue number	9
DOIs	https://doi.org/10.1093/qjmed/95.9.609
Publication status	Published - 2002

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Paracetamol toxicity: epidemiology, prevention and costs to the health-care system

Abstract

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