The enantio-pure 1D- and 1L-myo-inositol derivatives 3D and 3L have been used to prepare sodium 1D-6-O-(2-amino-2-deoxy-a-D-glucopyranosyl)-myo- inositol sn-2,3-dipalmitoyloxypropyl phosphate 21 and a related 1,6-disubstituted 1L-myo-inositol 28, respectively. The hydrogenphosphonate approach was effective in coupling together the phosphonolipid moiety 16 and the protected 6-O-(2-azido-2-deoxy-a-D-glucopyranosyl)-myo-inositols 15 and 24, respectively.
|Number of pages||7|
|Journal||Journal of the Chemical Society - Perkin Transactions 1|
|Publication status||Published - 1 Jan 1993|
Cottaz, S., Brimacombe, J. S., & Ferguson, M. A. J. (1993). Parasite glycoconjugates. Part 1: the synthesis of some early and related intermediates in the biosynthetic pathway of glycosyl-phosphatidylinositol membrane anchors. Journal of the Chemical Society - Perkin Transactions 1, (23), 2945-2951. https://doi.org/10.1039/P19930002945