Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan.

Andrei V. Nikolaev, Trevor J. Rutherford, Michael A. J. Ferguson, John S. Brimacombe

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    Abstract

    The model tetramannosyl triphosphate 7 and the hexaglycosyl triphosphate 8, which is a terminal fragment of the phosphoglycan portion of Leishmania donovani lipophosphoglycan, have been synthesized. Elongation of the chain was performed using the glycosyl hydrogenphosphonate method to couple together two phosphodiester blocks.

    Original languageEnglish
    Pages (from-to)1559-1566
    Number of pages8
    JournalJournal of the Chemical Society - Perkin Transactions 1
    Issue number13
    DOIs
    Publication statusPublished - 7 Jul 1996

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