Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan.

Andrei V.  Nikolaev; Trevor J. Rutherford; Michael A. J.  Ferguson; John S.  Brimacombe

doi:10.1039/P19960001559

Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan.

Andrei V. Nikolaev, Trevor J. Rutherford, Michael A. J. Ferguson, John S. Brimacombe

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

The model tetramannosyl triphosphate 7 and the hexaglycosyl triphosphate 8, which is a terminal fragment of the phosphoglycan portion of Leishmania donovani lipophosphoglycan, have been synthesized. Elongation of the chain was performed using the glycosyl hydrogenphosphonate method to couple together two phosphodiester blocks.

Original language	English
Pages (from-to)	1559-1566
Number of pages	8
Journal	Journal of the Chemical Society - Perkin Transactions 1
Issue number	13
DOIs	https://doi.org/10.1039/P19960001559
Publication status	Published - 7 Jul 1996

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Nikolaev, A. V., Rutherford, T. J., Ferguson, M. A. J., & Brimacombe, J. S. (1996). Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan. Journal of the Chemical Society - Perkin Transactions 1, (13), 1559-1566. https://doi.org/10.1039/P19960001559

Nikolaev, Andrei V. ; Rutherford, Trevor J. ; Ferguson, Michael A. J. et al. / Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates) : Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan. In: Journal of the Chemical Society - Perkin Transactions 1. 1996 ; No. 13. pp. 1559-1566.

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abstract = "The model tetramannosyl triphosphate 7 and the hexaglycosyl triphosphate 8, which is a terminal fragment of the phosphoglycan portion of Leishmania donovani lipophosphoglycan, have been synthesized. Elongation of the chain was performed using the glycosyl hydrogenphosphonate method to couple together two phosphodiester blocks.",

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Nikolaev, AV, Rutherford, TJ, Ferguson, MAJ & Brimacombe, JS 1996, 'Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan.', Journal of the Chemical Society - Perkin Transactions 1, no. 13, pp. 1559-1566. https://doi.org/10.1039/P19960001559

Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan. / Nikolaev, Andrei V. ; Rutherford, Trevor J.; Ferguson, Michael A. J. et al.
In: Journal of the Chemical Society - Perkin Transactions 1, No. 13, 07.07.1996, p. 1559-1566.

Research output: Contribution to journal › Article › peer-review

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AB - The model tetramannosyl triphosphate 7 and the hexaglycosyl triphosphate 8, which is a terminal fragment of the phosphoglycan portion of Leishmania donovani lipophosphoglycan, have been synthesized. Elongation of the chain was performed using the glycosyl hydrogenphosphonate method to couple together two phosphodiester blocks.

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Nikolaev AV, Rutherford TJ, Ferguson MAJ, Brimacombe JS. Parasite glycoconjugates. Part 5. Blockwise approach to oligo(glycosyl phosphates): Chemical synthesis of a terminal tris(glycobiosyl phosphate) fragment of Leishmania donovani antigenic lipophosphoglycan. Journal of the Chemical Society - Perkin Transactions 1. 1996 Jul 7;(13):1559-1566. doi: 10.1039/P19960001559