Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array

Han Wang, Yongqiang Qiu, Christine Demore, Sandy Cochran, Peter Glynne-Jones, Martyn Hill

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    3 Citations (Scopus)

    Abstract

    Ultrasonic standing wave manipulation has been proved to be a simple, robust technology to be integrated in microfluidic systems for a range of applications such as particle filtration and concentration, particle trapping and washing, and sensor enhancement. Here we report recent progress in the design, fabrication and experimental demonstration of an electronically controlled ultrasonic array device used for 1-D manipulation of particles along a microfluidic channel. In a previous paper [1], the particle manipulation feasibility has been demonstrated by a 12 element, 500 µm pitch array device. In this paper, an improved 30-element, 200 µm pitch array device made from PZ26 piezoelectric composite has been fabricated and connected to control electronics. The control system comprises a Xilinx Spartan 3a FPGA development board and bespoke analogue driving circuitry, designed for signal multiplexing for array element excitation. A rectangular capillary forming a half wavelength resonance microfluidic chamber was coupled to the array to make a multilayer planar resonator. Manipulation under electronic control was demonstrated with 10 µm fluorescent microspheres suspended in water.
    Original languageEnglish
    Title of host publication2012 IEEE International Ultrasonics Symposium
    PublisherIEEE
    Pages1-4
    Number of pages4
    ISBN (Print)9781467345613
    DOIs
    Publication statusPublished - 2012
    Event2012 IEEE International Ultrasonics Symposium (IUS) - Dresden, Germany
    Duration: 7 Oct 201210 Oct 2012
    http://ius2012.ifw-dresden.de/

    Conference

    Conference2012 IEEE International Ultrasonics Symposium (IUS)
    Abbreviated title2012 IEEE IUS
    CountryGermany
    CityDresden
    Period7/10/1210/10/12
    Internet address

    Fingerprint

    Microfluidics
    manipulators
    Ultrasonics
    electronic control
    Microspheres
    Multiplexing
    Washing
    ultrasonics
    Field programmable gate arrays (FPGA)
    Resonators
    Multilayers
    Electronic equipment
    Demonstrations
    washing
    Control systems
    Fabrication
    Wavelength
    multiplexing
    standing waves
    Sensors

    Keywords

    • array element excitation
    • size 200 mum
    • electronically controlled ultrasonic array device
    • rectangular capillary
    • microfluidics
    • size 500 mum
    • particle filtration and concentration
    • fluorescent microspheres
    • sensor enhancement
    • Arrays
    • particle trapping and washing
    • Microfluidics
    • microfluidic chamber
    • ultrasonic standing wave manipulation
    • microfluidic channel
    • multilayer planar resonator
    • 2-2 composite
    • Transducers
    • Acoustics
    • control system
    • planar resonator
    • signal multiplexing
    • electronic control
    • particle manipulation
    • Fluids
    • Field programmable gate arrays
    • PZ26 piezoelectric
    • FPGA
    • size 10 mum
    • microfluidic systems
    • bespoke analogue driving circuitry
    • piezoelectric devices
    • control electronics
    • Xilinx Spartan 3a FPGA development board
    • linear piezoelectric array
    • Array

    Cite this

    Wang, H., Qiu, Y., Demore, C., Cochran, S., Glynne-Jones, P., & Hill, M. (2012). Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array. In 2012 IEEE International Ultrasonics Symposium (pp. 1-4). IEEE. https://doi.org/10.1109/ULTSYM.2012.0500
    Wang, Han ; Qiu, Yongqiang ; Demore, Christine ; Cochran, Sandy ; Glynne-Jones, Peter ; Hill, Martyn. / Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array. 2012 IEEE International Ultrasonics Symposium. IEEE, 2012. pp. 1-4
    @inproceedings{b4a349ca149f42ae970ce76e07b90495,
    title = "Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array",
    abstract = "Ultrasonic standing wave manipulation has been proved to be a simple, robust technology to be integrated in microfluidic systems for a range of applications such as particle filtration and concentration, particle trapping and washing, and sensor enhancement. Here we report recent progress in the design, fabrication and experimental demonstration of an electronically controlled ultrasonic array device used for 1-D manipulation of particles along a microfluidic channel. In a previous paper [1], the particle manipulation feasibility has been demonstrated by a 12 element, 500 µm pitch array device. In this paper, an improved 30-element, 200 µm pitch array device made from PZ26 piezoelectric composite has been fabricated and connected to control electronics. The control system comprises a Xilinx Spartan 3a FPGA development board and bespoke analogue driving circuitry, designed for signal multiplexing for array element excitation. A rectangular capillary forming a half wavelength resonance microfluidic chamber was coupled to the array to make a multilayer planar resonator. Manipulation under electronic control was demonstrated with 10 µm fluorescent microspheres suspended in water.",
    keywords = "array element excitation, size 200 mum, electronically controlled ultrasonic array device, rectangular capillary, microfluidics, size 500 mum, particle filtration and concentration, fluorescent microspheres, sensor enhancement, Arrays, particle trapping and washing, Microfluidics, microfluidic chamber, ultrasonic standing wave manipulation, microfluidic channel, multilayer planar resonator, 2-2 composite, Transducers, Acoustics, control system, planar resonator, signal multiplexing, electronic control, particle manipulation, Fluids, Field programmable gate arrays, PZ26 piezoelectric, FPGA, size 10 mum, microfluidic systems, bespoke analogue driving circuitry, piezoelectric devices, control electronics, Xilinx Spartan 3a FPGA development board, linear piezoelectric array, Array",
    author = "Han Wang and Yongqiang Qiu and Christine Demore and Sandy Cochran and Peter Glynne-Jones and Martyn Hill",
    year = "2012",
    doi = "10.1109/ULTSYM.2012.0500",
    language = "English",
    isbn = "9781467345613",
    pages = "1--4",
    booktitle = "2012 IEEE International Ultrasonics Symposium",
    publisher = "IEEE",

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    Wang, H, Qiu, Y, Demore, C, Cochran, S, Glynne-Jones, P & Hill, M 2012, Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array. in 2012 IEEE International Ultrasonics Symposium. IEEE, pp. 1-4, 2012 IEEE International Ultrasonics Symposium (IUS), Dresden, Germany, 7/10/12. https://doi.org/10.1109/ULTSYM.2012.0500

    Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array. / Wang, Han; Qiu, Yongqiang; Demore, Christine; Cochran, Sandy; Glynne-Jones, Peter; Hill, Martyn.

    2012 IEEE International Ultrasonics Symposium. IEEE, 2012. p. 1-4.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

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    AU - Demore, Christine

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    AU - Glynne-Jones, Peter

    AU - Hill, Martyn

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    AB - Ultrasonic standing wave manipulation has been proved to be a simple, robust technology to be integrated in microfluidic systems for a range of applications such as particle filtration and concentration, particle trapping and washing, and sensor enhancement. Here we report recent progress in the design, fabrication and experimental demonstration of an electronically controlled ultrasonic array device used for 1-D manipulation of particles along a microfluidic channel. In a previous paper [1], the particle manipulation feasibility has been demonstrated by a 12 element, 500 µm pitch array device. In this paper, an improved 30-element, 200 µm pitch array device made from PZ26 piezoelectric composite has been fabricated and connected to control electronics. The control system comprises a Xilinx Spartan 3a FPGA development board and bespoke analogue driving circuitry, designed for signal multiplexing for array element excitation. A rectangular capillary forming a half wavelength resonance microfluidic chamber was coupled to the array to make a multilayer planar resonator. Manipulation under electronic control was demonstrated with 10 µm fluorescent microspheres suspended in water.

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    KW - piezoelectric devices

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    Wang H, Qiu Y, Demore C, Cochran S, Glynne-Jones P, Hill M. Particle manipulation in a microfluidic channel with an electronically controlled linear piezoelectric array. In 2012 IEEE International Ultrasonics Symposium. IEEE. 2012. p. 1-4 https://doi.org/10.1109/ULTSYM.2012.0500