Pathology of colorectal polyps and cancer

Lisa Johnston; Frank Carey

doi:10.1016/j.mpsur.2019.10.012

Pathology of colorectal polyps and cancer

Lisa Johnston, Frank Carey

Population Health and Genomics

Research output: Contribution to journal › Review article › peer-review

Abstract

Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.

Original language	English
Number of pages	6
Journal	Surgery (United Kingdom)
DOIs	https://doi.org/10.1016/j.mpsur.2019.10.012
Publication status	E-pub ahead of print - 25 Nov 2019

Keywords

Cancer biology
colorectal adenoma
colorectal carcinoma
polyp cancer
serrated polyp

Access to Document

10.1016/j.mpsur.2019.10.012

Link to publication in Scopus

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title = "Pathology of colorectal polyps and cancer",

abstract = "Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.",

keywords = "Cancer biology, colorectal adenoma, colorectal carcinoma, polyp cancer, serrated polyp",

author = "Lisa Johnston and Frank Carey",

year = "2019",

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AU - Johnston, Lisa

AU - Carey, Frank

PY - 2019/11/25

Y1 - 2019/11/25

N2 - Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.

AB - Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.

KW - Cancer biology

KW - colorectal adenoma

KW - colorectal carcinoma

KW - polyp cancer

KW - serrated polyp

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DO - 10.1016/j.mpsur.2019.10.012

M3 - Review article

AN - SCOPUS:85076468812

JO - Surgery (Oxford)

JF - Surgery (Oxford)

SN - 0263-9319

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