Pathology of colorectal polyps and cancer

TY - JOUR

T1 - Pathology of colorectal polyps and cancer

AU - Johnston, Lisa

AU - Carey, Frank

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.

AB - Colorectal adenomas and cancers are common. Diagnosis and management of these lesions requires close clinical-pathological correlation. This article emphasizes clinically important issues in management of adenomas, including serrated lesions, and early stage cancers removed by local excision. Pathological interpretation and staging of formal resection specimens is also discussed. The biology of colorectal cancer is emphasized, particularly reflecting the need for molecular analysis to guide adjuvant oncological treatment.

KW - Cancer biology

KW - colorectal adenoma

KW - colorectal carcinoma

KW - polyp cancer

KW - serrated polyp

UR - https://www.scopus.com/pages/publications/85076468812

U2 - 10.1016/j.mpsur.2019.10.012

DO - 10.1016/j.mpsur.2019.10.012

M3 - Review article

AN - SCOPUS:85076468812

SN - 0263-9319

VL - 38

JO - Surgery (United Kingdom)

JF - Surgery (United Kingdom)

IS - 1

ER -