PC12 Interaction with Magnetic Nanotubes:  Effects on Viability, Cell Differentiation and Cell Translocation Induced by a Magnetic Field

Orazio Vittorio; Vittoria Raffa; Cristina Riggio; Andrea Pietrabissa; Alfred Cuschieri

PC12 Interaction with Magnetic Nanotubes: Effects on Viability, Cell Differentiation and Cell Translocation Induced by a Magnetic Field

Orazio Vittorio
, Vittoria Raffa
, Cristina Riggio
, Andrea Pietrabissa
, Alfred Cuschieri

Research output: Contribution to journal › Article › peer-review

Abstract

In this paper we used Multi Wall Carbon Nanotubes (MWCNTs) containing 3% of residuals and impurities of Fe, Al, and Zn. MWCNTs, by virtue of Fe at their tips, are able to respond to the effects of external magnetic fields. We demonstrated that MWCNTs interact with PC12 cells without compromising their viability and differentiation with outgrowth of neurites. We also document that when exposed to a magnetic field, both undifferentiated and differentiated PC12 cells cultured in CNT-containing medium solution are able to move towards the magnetic source.

Original language	English
Pages (from-to)	337-344
Number of pages	8
Journal	Current Nanoscience
Volume	7
Issue number	3
Publication status	Published - Jun 2011

Keywords

Nanoparticles
magnetic materials
cell displacement
neuronal differentiation
WALLED CARBON NANOTUBES
NEURONAL GROWTH
IN-VITRO
PEPTIDES

Cite this

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title = "PC12 Interaction with Magnetic Nanotubes: Effects on Viability, Cell Differentiation and Cell Translocation Induced by a Magnetic Field",

abstract = "In this paper we used Multi Wall Carbon Nanotubes (MWCNTs) containing 3\% of residuals and impurities of Fe, Al, and Zn. MWCNTs, by virtue of Fe at their tips, are able to respond to the effects of external magnetic fields. We demonstrated that MWCNTs interact with PC12 cells without compromising their viability and differentiation with outgrowth of neurites. We also document that when exposed to a magnetic field, both undifferentiated and differentiated PC12 cells cultured in CNT-containing medium solution are able to move towards the magnetic source.",

keywords = "Nanoparticles, magnetic materials, cell displacement, neuronal differentiation, WALLED CARBON NANOTUBES, NEURONAL GROWTH, IN-VITRO, PEPTIDES",

author = "Orazio Vittorio and Vittoria Raffa and Cristina Riggio and Andrea Pietrabissa and Alfred Cuschieri",

year = "2011",

month = jun,

language = "English",

volume = "7",

pages = "337--344",

journal = "Current Nanoscience",

issn = "1573-4137",

publisher = "Bentham Science Publishers",

number = "3",

}

TY - JOUR

T1 - PC12 Interaction with Magnetic Nanotubes

T2 - Effects on Viability, Cell Differentiation and Cell Translocation Induced by a Magnetic Field

AU - Vittorio, Orazio

AU - Raffa, Vittoria

AU - Riggio, Cristina

AU - Pietrabissa, Andrea

AU - Cuschieri, Alfred

PY - 2011/6

Y1 - 2011/6

N2 - In this paper we used Multi Wall Carbon Nanotubes (MWCNTs) containing 3% of residuals and impurities of Fe, Al, and Zn. MWCNTs, by virtue of Fe at their tips, are able to respond to the effects of external magnetic fields. We demonstrated that MWCNTs interact with PC12 cells without compromising their viability and differentiation with outgrowth of neurites. We also document that when exposed to a magnetic field, both undifferentiated and differentiated PC12 cells cultured in CNT-containing medium solution are able to move towards the magnetic source.

AB - In this paper we used Multi Wall Carbon Nanotubes (MWCNTs) containing 3% of residuals and impurities of Fe, Al, and Zn. MWCNTs, by virtue of Fe at their tips, are able to respond to the effects of external magnetic fields. We demonstrated that MWCNTs interact with PC12 cells without compromising their viability and differentiation with outgrowth of neurites. We also document that when exposed to a magnetic field, both undifferentiated and differentiated PC12 cells cultured in CNT-containing medium solution are able to move towards the magnetic source.

KW - Nanoparticles

KW - magnetic materials

KW - cell displacement

KW - neuronal differentiation

KW - WALLED CARBON NANOTUBES

KW - NEURONAL GROWTH

KW - IN-VITRO

KW - PEPTIDES

M3 - Article

SN - 1573-4137

VL - 7

SP - 337

EP - 344

JO - Current Nanoscience

JF - Current Nanoscience

IS - 3

ER -

PC12 Interaction with Magnetic Nanotubes: Effects on Viability, Cell Differentiation and Cell Translocation Induced by a Magnetic Field

Abstract

Keywords

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