Abstract
Pellagra is a clinical syndrome caused by a deficiency of niacin (nicotinic acid) and/or its precursor tryptophan. The cardinal manifestations are 4 D's- dermatitis, diarrhoea, dementia and in worst case death. Increased use of isoniazid prophylaxis along with antiretroviral therapy in countries where latent tuberculosis is common has been associated with increased presentations with pellagra.
Original language | English |
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Pages (from-to) | 99-104 |
Number of pages | 6 |
Journal | Photodermatology, Photoimmunology & Photomedicine |
Volume | 37 |
Issue number | 2 |
Early online date | 20 Jan 2021 |
DOIs | |
Publication status | Published - 2 Feb 2021 |
Keywords
- Hartnup's disease
- carcinoid syndrome
- drug-induced pellagra
- isoniazid
- niacin
- nutrition
- pellagra
- photosensitivity
- tryptophan
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Radiology Nuclear Medicine and imaging
- Dermatology