Phosphorylation of synaptic vesicle protein 2A at Thr84 by casein kinase 1 family kinases controls the specific retrieval of synaptotagmin-1

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• Finished

  State-of-the-Art Facilities for Structural Biology at the University of Dundee

  Hunter, B. (Investigator), Lilley, D. (Investigator), Owen-Hughes, T. (Investigator), Wyatt, P. (Investigator) & van Aalten, D. (Investigator)

  1/03/12 → 28/02/17

  Project: Research

  • Proteolysis Targeting chimera (PROTAC) 100%
  • Crystal Structure 82%
  • Enzyme 73%
  • Proteolysis 70%
  • Ternary Complex 60%

• Aref#d: 21318. Molecular Mechanisms of O-GlcNAc Signalling (Senior Fellowship Renewal)

  van Aalten, D. (Investigator)

  1/06/09 → 29/02/16

  Project: Research

  • O-linked N-acetylglucosamine (O-GlcNAc) 100%
  • Transferase 95%
  • O-GlcNAcase 93%
  • Enzyme 80%
  • O-GlcNAc Transferase 77%