Physical education - New technologies for mapping plant genomes

Robert Waugh; Paul H. Dear; Wayne Powell; Gordon C. Machray

doi:10.1016/S1360-1385(02)02373-7

Physical education - New technologies for mapping plant genomes

Robert Waugh (Lead / Corresponding author), Paul H. Dear, Wayne Powell, Gordon C. Machray

Plant Sciences

Research output: Contribution to journal › Short survey › peer-review

8 Citations (Scopus)

Abstract

Locating DNA sequences to specific chromosomal segments is essential for associating genes with phenotypes. It is routinely achieved by segregation analysis using meiotic mapping populations that have also been used to collect phenotypic information. However, meiotic mapping is struggling to cope with the shear volume of sequences emerging from high-throughput (HTP) gene-discovery programs. We describe two approaches, Radiation Hybrid and 'HAPPY' mapping, which, in conjunction with meiotic mapping, represent valuable HTP tools in the quest to link genes to phenotypes.

Original language	English
Pages (from-to)	521-523
Number of pages	3
Journal	Trends in Plant Science
Volume	7
Issue number	12
DOIs	https://doi.org/10.1016/S1360-1385(02)02373-7
Publication status	Published - 1 Dec 2002

ASJC Scopus subject areas

Plant Science

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10.1016/S1360-1385(02)02373-7

Cite this

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AU - Waugh, Robert

AU - Dear, Paul H.

AU - Powell, Wayne

AU - Machray, Gordon C.

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N2 - Locating DNA sequences to specific chromosomal segments is essential for associating genes with phenotypes. It is routinely achieved by segregation analysis using meiotic mapping populations that have also been used to collect phenotypic information. However, meiotic mapping is struggling to cope with the shear volume of sequences emerging from high-throughput (HTP) gene-discovery programs. We describe two approaches, Radiation Hybrid and 'HAPPY' mapping, which, in conjunction with meiotic mapping, represent valuable HTP tools in the quest to link genes to phenotypes.

AB - Locating DNA sequences to specific chromosomal segments is essential for associating genes with phenotypes. It is routinely achieved by segregation analysis using meiotic mapping populations that have also been used to collect phenotypic information. However, meiotic mapping is struggling to cope with the shear volume of sequences emerging from high-throughput (HTP) gene-discovery programs. We describe two approaches, Radiation Hybrid and 'HAPPY' mapping, which, in conjunction with meiotic mapping, represent valuable HTP tools in the quest to link genes to phenotypes.

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JO - Trends in Plant Science

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ER -

Physical education - New technologies for mapping plant genomes

Abstract

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