Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis

G J Beckett; P C Hayes; A J Hussey; I A Bouchier; J D Hayes

doi:10.1016/0009-8981(87)90396-2

Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis

G J Beckett, P C Hayes, A J Hussey, I A Bouchier, J D Hayes

Research output: Contribution to journal › Article › peer-review

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Abstract

Hepatocellular damage has been assessed in 54 patients with biopsy proven alcoholic cirrhosis by measuring the activity of aspartate aminotransferase (AST) and the concentrations of glutathione S-transferase B1B1 (GST B1B1) and B2B2 (GST B2B2) in serum. The levels of AST, GST B1B1, or GST B2B2 were abnormal in 28, 28 and 17 patients respectively but abnormalities in AST and GST measurements appeared to identify different populations of patients.

Original language	English
Pages (from-to)	85-9
Number of pages	5
Journal	Clinica Chimica Acta
Volume	169
Issue number	1
DOIs	https://doi.org/10.1016/0009-8981(87)90396-2
Publication status	Published - 30 Oct 1987

Keywords

Aspartate Aminotransferases/blood
Glutathione Transferase/blood
Humans
Isoenzymes/blood
Liver Cirrhosis, Alcoholic/enzymology
Radioimmunoassay

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10.1016/0009-8981(87)90396-2

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title = "Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis",

abstract = "Hepatocellular damage has been assessed in 54 patients with biopsy proven alcoholic cirrhosis by measuring the activity of aspartate aminotransferase (AST) and the concentrations of glutathione S-transferase B1B1 (GST B1B1) and B2B2 (GST B2B2) in serum. The levels of AST, GST B1B1, or GST B2B2 were abnormal in 28, 28 and 17 patients respectively but abnormalities in AST and GST measurements appeared to identify different populations of patients.",

keywords = "Aspartate Aminotransferases/blood, Glutathione Transferase/blood, Humans, Isoenzymes/blood, Liver Cirrhosis, Alcoholic/enzymology, Radioimmunoassay",

author = "Beckett, {G J} and Hayes, {P C} and Hussey, {A J} and Bouchier, {I A} and Hayes, {J D}",

year = "1987",

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doi = "10.1016/0009-8981(87)90396-2",

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T1 - Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis

AU - Beckett, G J

AU - Hayes, P C

AU - Hussey, A J

AU - Bouchier, I A

AU - Hayes, J D

PY - 1987/10/30

Y1 - 1987/10/30

N2 - Hepatocellular damage has been assessed in 54 patients with biopsy proven alcoholic cirrhosis by measuring the activity of aspartate aminotransferase (AST) and the concentrations of glutathione S-transferase B1B1 (GST B1B1) and B2B2 (GST B2B2) in serum. The levels of AST, GST B1B1, or GST B2B2 were abnormal in 28, 28 and 17 patients respectively but abnormalities in AST and GST measurements appeared to identify different populations of patients.

AB - Hepatocellular damage has been assessed in 54 patients with biopsy proven alcoholic cirrhosis by measuring the activity of aspartate aminotransferase (AST) and the concentrations of glutathione S-transferase B1B1 (GST B1B1) and B2B2 (GST B2B2) in serum. The levels of AST, GST B1B1, or GST B2B2 were abnormal in 28, 28 and 17 patients respectively but abnormalities in AST and GST measurements appeared to identify different populations of patients.

KW - Aspartate Aminotransferases/blood

KW - Glutathione Transferase/blood

KW - Humans

KW - Isoenzymes/blood

KW - Liver Cirrhosis, Alcoholic/enzymology

KW - Radioimmunoassay

U2 - 10.1016/0009-8981(87)90396-2

DO - 10.1016/0009-8981(87)90396-2

M3 - Article

C2 - 3677438

SN - 0009-8981

VL - 169

SP - 85

EP - 89

JO - Clinica Chimica Acta

JF - Clinica Chimica Acta

IS - 1

ER -

Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis

Abstract

Keywords

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