"Plasmo2D": An Ancillary Proteomic Tool to Aid Identification of Proteins from Plasmodium falciparum

Amit Khachane, Ranjit Kumar, Sanyam Jain, Samta Jain, Gowrishankar Banumathy, Varsha Singh, Saurabh Nagpal, Utpal Tatu (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Bioinformatics tools to aid gene and protein sequence analysis have become an integral part of biology in the post-genomic era. Release of the Plasmodium falciparum genome sequence has allowed biologists to define the gene and the predicted protein content as well as their sequences in the parasite. Using p/ and molecular weight as characteristics unique to each protein, we have developed a bioinformatics tool to aid identification of proteins from Plasmodium falciparum. The tool makes use of a Virtual 2-DE generated by plotting all of the proteins from the Plasmodium database on a p/ versus molecular weight scale. Proteins are identified by comparing the position of migration of desired protein spots from an experimental 2-DE and that on a virtual 2-DE. The procedure has been automated in the form of user-friendly software called "Plasmo2D".

Original languageEnglish
Pages (from-to)2369-2374
Number of pages6
JournalJournal of Proteome Research
Issue number6
Early online date18 Oct 2005
Publication statusPublished - 1 Dec 2005


  • Bioinformatics
  • Heat shock proteins
  • Malaria
  • Plasmo2D
  • Proteomics

ASJC Scopus subject areas

  • General Chemistry
  • Biochemistry


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