Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72

Keyphrases

• Binding Protein 100%
• Amyotrophic Lateral Sclerosis 100%
• Poly(A) 100%
• TDP-43 Inclusions 100%
• C9orf72 100%
• TAR DNA-binding Protein 43 (TDP-43) 25%
• Colocalization 16%
• Spinal Motor Neurons 16%
• Fused in Sarcoma 16%
• Genetic mutation 8%
• Paralysis 8%
• Motor Neuron Disease 8%
• Transactivity 8%
• Cytoplasmic Inclusions 8%
• RNA-binding Protein 8%
• DNA-binding Proteins 8%
• Causative Gene 8%
• Patient Cohort 8%
• Clinical Disease 8%
• Disease Onset 8%
• Adult-onset 8%
• Proteomic Profile 8%
• Translational Arrest 8%
• Repeat Expansion 8%
• Stress Granules 8%
• ATXN2 8%
• C9orf72 Expansion 8%
• Polyglutamine Repeat 8%
• GGGGCC 8%
• Basophilic Inclusion Body Disease 8%
• Hexanucleotide Repeat Expansion 8%
• Neuronal Inclusions 8%

Biochemistry, Genetics and Molecular Biology

• Synapsin I 100%
• Poly(A)-Binding Protein 100%
• Transactive Response Dna Binding Protein-43 100%
• C9orf72 100%
• Motor Neuron 60%
• Gene Mutation 20%
• RNA 20%
• RNA-binding Protein 20%
• Stress Granule 20%
• ATXN2 20%
• DNA-binding Protein 20%
• Proteomics 20%

Neuroscience

• Synapsin I 100%
• Amyotrophic Lateral Sclerosis 100%
• Poly(A)-Binding Protein 100%
• Proteomics 9%
• Polyglutamine 9%
• Gene Mutation 9%
• DNA-binding Protein 9%
• Motor Neuron Disease 9%
• Pathology of Amyotrophic Lateral Sclerosis 9%
• RNA-binding Protein 9%