Portable Microcontroller-Based Instrument for Near Infrared Spectroscopy

TY - GEN

T1 - Portable Microcontroller-Based Instrument for Near Infrared Spectroscopy

AU - Giardini, Mario E.

AU - Corti, Mario

AU - Lago, Paolo

AU - Gelmetti, Andrea

PY - 2000/5/3

Y1 - 2000/5/3

N2 - Near IR Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. In particular, the technique can be particularly useful for muscular functional monitoring. We present a portable NIRS research-grade acquisition system prototype, strictly dedicate to low-noise measurements during muscular exercise. The prototype is able to control four LED sources and a detector. Such a number of sources allows for multipoint measurements or for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3 oxidation. The LEDs and the detector are mounted on separate probes, which carry also the relevant drivers and preamplifiers. By employing surface-mount technologies, probe size and weight are kept to a minimum. A single-chip mixed-signal RISC microcontroller performs source-to- detector multiplexing with a digital correlation technique. The acquired data are stored on an on-board 64 K EEPROM bank, and can be subsequently uploaded to a personal computer via serial port for further analysis. The resulting instrument is compact and lightweight. Preliminary test of the prototype on oxygen consumption during tourniquet- induced forearm ischaemia show adequate detectivity and time response.

AB - Near IR Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues. In particular, the technique can be particularly useful for muscular functional monitoring. We present a portable NIRS research-grade acquisition system prototype, strictly dedicate to low-noise measurements during muscular exercise. The prototype is able to control four LED sources and a detector. Such a number of sources allows for multipoint measurements or for multi-wavelength spectroscopy of tissue constituents other than oxygen, such as cytochrome aa3 oxidation. The LEDs and the detector are mounted on separate probes, which carry also the relevant drivers and preamplifiers. By employing surface-mount technologies, probe size and weight are kept to a minimum. A single-chip mixed-signal RISC microcontroller performs source-to- detector multiplexing with a digital correlation technique. The acquired data are stored on an on-board 64 K EEPROM bank, and can be subsequently uploaded to a personal computer via serial port for further analysis. The resulting instrument is compact and lightweight. Preliminary test of the prototype on oxygen consumption during tourniquet- induced forearm ischaemia show adequate detectivity and time response.

KW - Near-infrared spectroscopy

KW - NIRS

U2 - 10.1117/12.384910

DO - 10.1117/12.384910

M3 - Conference contribution

VL - 3911

T3 - Proceedings of SPIE - The International Society for Optical Engineering

SP - 250

EP - 255

BT - Biomedical Diagnostic, Guidance, and Surgical Assist Systems II

A2 - Vo-Dinh, Tuan

A2 - Grundfest, Warren S.

A2 - Benaron, David A.

PB - SPIE-International Society for Optical Engineering

T2 - BIOS 2000 The International Symposium on Biomedical Optics

Y2 - 22 January 2000 through 28 January 2000

ER -