Post-exposure prophylaxis following occupational exposure to HIV and hepatitis B: An analysis of a 12-year record in a Nigerian tertiary hospital

Salisu Abubakar, Garba Iliyasu, Farouq Muhammad Dayyab (Lead / Corresponding author), Salisu Inuwa, Rabiu Alhassan Tudun Wada, Nasiru Magaji Sadiq, Muktar Ahmed Gadanya, Abdulrahman Abba Sheshe, Mohammad Sani Mijinyawa, Abdulrazaq Garba Habib

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Background: Healthcare workers (HCWs) have an increased risk of occupational exposure to blood-borne pathogens.

Aims/objectives: We aim to examine the utilisation and outcome of post-exposure prophylaxis (PEP) for both HIV and hepatitis B (HBV) among HCWs.

Methods: This was a retrospective study conducted in a tertiary hospital in North-Western Nigeria. We reviewed data on HIV or HBV PEP given to HCWs between 2004 and 2016.

Results: A total of 115 HCWs presented for PEP during the study period. Intern doctors were the most exposed group (40/115; 34.8%). There were 86/115 (74.8%) needle stick exposures. While 53/115 (46.1%) of the sources of exposure were HIV-positive, 9/115(7.83%) were HBV-positive. Zidovudine-based regimen (40/70) was the most commonly prescribed. No seroconversion occurred among those that completed PEP treatment and follow-up.

Discussion: No seroconversion occurred among those that received either or both HIV and HBV PEP and completed PEP treatment.
Original languageEnglish
Pages (from-to)184-189
Number of pages6
JournalJournal of Infection Prevention
Volume19
Issue number4
Early online date17 Dec 2017
DOIs
Publication statusPublished - 2018

Keywords

  • Human immunodeficiency virus (HIV)
  • Infection control
  • Vaccination

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Advanced and Specialised Nursing
  • Infectious Diseases

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