Posteroanterior cephalometric analysis of the parental craniofacial morphology in orofacial clefting

G. T. McIntyre, P. A. Mossey

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    Objective: To evaluate the parental craniofacial morphology in orofacial clefting (OFC). Design: Case-control posteroanterior cephalometric study. Setting: The Department of Orthodontics, University of Dundee Dental School, Scotland, United Kingdom. Participants: Ninety-two parents from a completely ascertained sample of 286 Scottish babies with nonsyndromic OFC and 43 comparison group volunteers from the University of Dundee Dental School. Main Outcome Measures: A conventional cephalometric analysis was used to measure linear distances and their ratios, angles, and areas. Two-sample Student's t tests and a discriminant analysis were applied to the data, and the clinically important statistically significant variables were identified using an accepted protocol. Results: Sixty-four linear distances, 10 ratios, 52 angles, and 7 areas statistically significantly differed between the parental and comparison groups (p < .01). Of these, 62 linear distances (22%), 9 ratios (45%), 41 angles (41%), and 6 areas (24%) were clinically important. Asymmetry was a feature of the results. Canonical variates analysis correctly classified 91.3% of the parental group and 90.6% of the comparison group using a series of 36 variables. Conclusions: The parental craniofacial morphology in OFC differs significantly from the noncleft population. A larger superolateral face and smaller central midface and, in particular, a clinically significantly smaller maxillary width, in conjunction with skeletal asymmetry, characterize the parents of Scottish children with OFC. These features may be of morphogenetic importance in the etiopathogenesis of OFC in this ethnic group.
    Original languageEnglish
    Pages (from-to)416-425
    Number of pages10
    JournalCleft Palate-Craniofacial Journal
    Volume40
    Issue number4
    DOIs
    Publication statusPublished - 2003

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    Cephalometry
    Dental Schools
    Parents
    Scotland
    Discriminant Analysis
    Orthodontics
    Ethnic Groups
    Volunteers
    Outcome Assessment (Health Care)
    Students
    Population

    Keywords

    • Orofacial clefting
    • PA cephalogram
    • PA cephalometric analysis
    • Parents

    Cite this

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    title = "Posteroanterior cephalometric analysis of the parental craniofacial morphology in orofacial clefting",
    abstract = "Objective: To evaluate the parental craniofacial morphology in orofacial clefting (OFC). Design: Case-control posteroanterior cephalometric study. Setting: The Department of Orthodontics, University of Dundee Dental School, Scotland, United Kingdom. Participants: Ninety-two parents from a completely ascertained sample of 286 Scottish babies with nonsyndromic OFC and 43 comparison group volunteers from the University of Dundee Dental School. Main Outcome Measures: A conventional cephalometric analysis was used to measure linear distances and their ratios, angles, and areas. Two-sample Student's t tests and a discriminant analysis were applied to the data, and the clinically important statistically significant variables were identified using an accepted protocol. Results: Sixty-four linear distances, 10 ratios, 52 angles, and 7 areas statistically significantly differed between the parental and comparison groups (p < .01). Of these, 62 linear distances (22{\%}), 9 ratios (45{\%}), 41 angles (41{\%}), and 6 areas (24{\%}) were clinically important. Asymmetry was a feature of the results. Canonical variates analysis correctly classified 91.3{\%} of the parental group and 90.6{\%} of the comparison group using a series of 36 variables. Conclusions: The parental craniofacial morphology in OFC differs significantly from the noncleft population. A larger superolateral face and smaller central midface and, in particular, a clinically significantly smaller maxillary width, in conjunction with skeletal asymmetry, characterize the parents of Scottish children with OFC. These features may be of morphogenetic importance in the etiopathogenesis of OFC in this ethnic group.",
    keywords = "Orofacial clefting, PA cephalogram, PA cephalometric analysis, Parents",
    author = "McIntyre, {G. T.} and Mossey, {P. A.}",
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    doi = "10.1597/1545-1569(2003)040<0416:PCAOTP>2.0.CO;2",
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    }

    Posteroanterior cephalometric analysis of the parental craniofacial morphology in orofacial clefting. / McIntyre, G. T.; Mossey, P. A.

    In: Cleft Palate-Craniofacial Journal, Vol. 40, No. 4, 2003, p. 416-425.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Posteroanterior cephalometric analysis of the parental craniofacial morphology in orofacial clefting

    AU - McIntyre, G. T.

    AU - Mossey, P. A.

    N1 - dc.publisher: The American Cleft Palate-Craniofacial Association

    PY - 2003

    Y1 - 2003

    N2 - Objective: To evaluate the parental craniofacial morphology in orofacial clefting (OFC). Design: Case-control posteroanterior cephalometric study. Setting: The Department of Orthodontics, University of Dundee Dental School, Scotland, United Kingdom. Participants: Ninety-two parents from a completely ascertained sample of 286 Scottish babies with nonsyndromic OFC and 43 comparison group volunteers from the University of Dundee Dental School. Main Outcome Measures: A conventional cephalometric analysis was used to measure linear distances and their ratios, angles, and areas. Two-sample Student's t tests and a discriminant analysis were applied to the data, and the clinically important statistically significant variables were identified using an accepted protocol. Results: Sixty-four linear distances, 10 ratios, 52 angles, and 7 areas statistically significantly differed between the parental and comparison groups (p < .01). Of these, 62 linear distances (22%), 9 ratios (45%), 41 angles (41%), and 6 areas (24%) were clinically important. Asymmetry was a feature of the results. Canonical variates analysis correctly classified 91.3% of the parental group and 90.6% of the comparison group using a series of 36 variables. Conclusions: The parental craniofacial morphology in OFC differs significantly from the noncleft population. A larger superolateral face and smaller central midface and, in particular, a clinically significantly smaller maxillary width, in conjunction with skeletal asymmetry, characterize the parents of Scottish children with OFC. These features may be of morphogenetic importance in the etiopathogenesis of OFC in this ethnic group.

    AB - Objective: To evaluate the parental craniofacial morphology in orofacial clefting (OFC). Design: Case-control posteroanterior cephalometric study. Setting: The Department of Orthodontics, University of Dundee Dental School, Scotland, United Kingdom. Participants: Ninety-two parents from a completely ascertained sample of 286 Scottish babies with nonsyndromic OFC and 43 comparison group volunteers from the University of Dundee Dental School. Main Outcome Measures: A conventional cephalometric analysis was used to measure linear distances and their ratios, angles, and areas. Two-sample Student's t tests and a discriminant analysis were applied to the data, and the clinically important statistically significant variables were identified using an accepted protocol. Results: Sixty-four linear distances, 10 ratios, 52 angles, and 7 areas statistically significantly differed between the parental and comparison groups (p < .01). Of these, 62 linear distances (22%), 9 ratios (45%), 41 angles (41%), and 6 areas (24%) were clinically important. Asymmetry was a feature of the results. Canonical variates analysis correctly classified 91.3% of the parental group and 90.6% of the comparison group using a series of 36 variables. Conclusions: The parental craniofacial morphology in OFC differs significantly from the noncleft population. A larger superolateral face and smaller central midface and, in particular, a clinically significantly smaller maxillary width, in conjunction with skeletal asymmetry, characterize the parents of Scottish children with OFC. These features may be of morphogenetic importance in the etiopathogenesis of OFC in this ethnic group.

    KW - Orofacial clefting

    KW - PA cephalogram

    KW - PA cephalometric analysis

    KW - Parents

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    DO - 10.1597/1545-1569(2003)040<0416:PCAOTP>2.0.CO;2

    M3 - Article

    VL - 40

    SP - 416

    EP - 425

    JO - Cleft Palate-Craniofacial Journal

    JF - Cleft Palate-Craniofacial Journal

    SN - 1055-6656

    IS - 4

    ER -