Postnatal growth in preterm infants and later health outcomes: a systematic review

Ken K. Ong (Lead / Corresponding author), Kathy Kennedy, Eurídice Castañeda-Gutiérrez, Stewart Forsyth, Keith M. Godfrey, Berthold Koletzko, Marie E. Latulippe, Susan E. Ozanne, Ricardo Rueda, Marieke H. Schoemaker, Eline M. van der Beek, Stef van Buuren, Mary Fewtrell

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    230 Citations (Scopus)
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    UNLABELLED: In preterm infants, poor postnatal growth is associated with adverse neurocognitive outcomes; conversely, rapid postnatal growth is supposedly harmful for future development of metabolic diseases.

    CONCLUSION: In this systematic review, observational studies reported consistent positive associations between postnatal weight or head growth and neurocognitive outcomes; however, there was limited evidence from the few intervention studies. Evidence linking postnatal weight gain to later adiposity and other cardiovascular disease risk factors in preterm infants was also limited.

    Original languageEnglish
    Pages (from-to)974-986
    Number of pages13
    JournalActa Paediatrica
    Issue number10
    Early online date15 Jul 2015
    Publication statusPublished - Oct 2015


    • Adiposity
    • Child development
    • Humans
    • Infant, Newborn
    • Infant, Premature
    • Insulin resistance
    • Neurocognitive disorders
    • Risk factors


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