Postoperative Pain, COX-2 Inhibitors

Ian Power, Lesley A. Colvin

Research output: Chapter in Book/Report/Conference proceedingChapter


COX-2 inhibitors are anti-inflammatory analgesics that act by specific inhibition of one of the isoenzymes involved in prostaglandin synthesis, cyclooxygenase 2 (COX-2). These drugs were developed as an alternative to traditional NSAIDs ( NSAIDs, Survey), with the aim of maintaining or improving efficacy and reducing adverse effects.

Original languageEnglish
Title of host publicationEncyclopedia of Pain
EditorsGerald F. Gebhart, Robert F. Schmidt
ISBN (Electronic)978-3-642-28753-4
ISBN (Print)978-3-642-28752-7
Publication statusPublished - 2013

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