Potent and selective chemical probe of hypoxic signaling downstream of HIF-α hydroxylation via VHL inhibition

Julianty Frost, Carles Galdeano, Pedro Soares, Morgan S. Gadd, Katarzyna M. Grzes, Lucy Ellis, Ola Epemolu, Satoko Shimamura, Marcus Bantscheff, Paola Grandi, Kevin D. Read, Doreen A. Cantrell, Sonia Rocha, Alessio Ciulli (Lead / Corresponding author)

Research output: Contribution to journal › Article › peer-review

127 Citations (Scopus)

203 Downloads (Pure)

3 results

Finished
DrugE3CRL's: Probing Druggability of Multisubunit Complexes: E3 Cullin RING Ligases (ERC Starting Grant)
Ciulli, A.
COMMISSION OF THE EUROPEAN COMMUNITIES
1/05/13 → 30/04/18
Project: Research
Dissecting and Exploiting Molecular Recognition at Protein-Protein Interfaces (David Phillips Fellowship)
Ciulli, A.
Biotechnology and Biological Sciences Research Council
8/04/13 → 7/07/15
Project: Research
Design of Orthogonal Molecular Probes Targeting Engineered Von-Hippel Lindau (VHL) E3 Ubiquitin Ligase for the Control of Intercellular Protein Levels
Ciulli, A.
COMMISSION OF THE EUROPEAN COMMUNITIES
8/04/13 → 7/04/15
Project: Research