Practical considerations for conducting dental clinical trials in primary care

J. M. Martin-Kerry (Lead / Corresponding author), T. J. Lamont, A. Keightley, H. Calache, R. Martin, R. Floate, K. Princi, A. M. De Silva

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)
1121 Downloads (Pure)


There is increasing importance placed on conducting clinical trials in dentistry to provide a robust evidence base for the treatment provided, and models of care delivered. However, providing the evidence upon which to base such decisions is not straightforward, as the conduct of these trials is complex. Currently, only limited information is available about the strategies to deliver successful clinical trials in primary care settings, and even less available on dental clinical trials. Considerable knowledge and experience is lost once a trial is completed as details about effective management of a trial are generally not reported or disseminated to trial managers and researchers. This leads to loss of vital knowledge that could assist with the effective delivery of new trials. The aim of this study is to examine the conduct and delivery of five dental clinical trials across both Australia and the UK and identify the various factors that impacted upon their implementation. Findings suggest that early stakeholder engagement, and well-designed and managed trials, lead to improved outcomes for researchers, clinic staff and patients, and increases the potential for future dissemination and translation of information into practice.

Original languageEnglish
Pages (from-to)629-634
Number of pages6
JournalBritish Dental Journal
Issue number11
Early online date12 Jun 2015
Publication statusPublished - Jun 2015


  • dental trial
  • methodology
  • challenges
  • primary care

ASJC Scopus subject areas

  • General Medicine
  • General Dentistry


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