Predictors of exercise capacity and everyday activity in older heart failure patients

TY - JOUR

T1 - Predictors of exercise capacity and everyday activity in older heart failure patients

AU - Witham, Miles D.

AU - Argo, Ishbel S.

AU - Johnston, Derek W.

AU - Struthers, Allan D.

AU - McMurdo, Marion E. T.

N1 - dc.publisher: Oxford University Press dc.description.sponsorship: The Health Foundation (formerly PPP Health Foundation) 2006/918

PY - 2006/3

Y1 - 2006/3

N2 - Background: Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group. Aims: To explore predictors of exercise capacity and daily activity in older, frail heart failure patients. Methods: Analysis of prospectively collected data from a cohort of 82 patients aged 70 years and over, enrolled in a randomised controlled trial of exercise in heart failure patients. Pathophysiological, demographic, psychological and social factors were analysed by multivariate regression to determine predictors of exercise capacity (6-min walk distance) and daily activity (daily accelerometer counts). Results: Between 49% and 55% of the variance in 6-min walk distance was explained by variables including New York Heart Association class, depression score, attitude to ageing and use of walking aids. Only 11% to 26% of the variance in accelerometer scores was explained by the model; 6-min walk distance was the only consistent predictor of daily activity. Conclusions: Physical, psychological and attitudinal variables contribute to variance of the 6-min walk. Six-minute walk distance predicts a small amount of the variance in daily activity, but the majority of variance in daily activity remains unexplained and requires further investigation.

AB - Background: Exercise capacity and daily activity are key outcomes for older, frail heart failure patients. Little is known about the determinants of these outcomes in this patient group. Aims: To explore predictors of exercise capacity and daily activity in older, frail heart failure patients. Methods: Analysis of prospectively collected data from a cohort of 82 patients aged 70 years and over, enrolled in a randomised controlled trial of exercise in heart failure patients. Pathophysiological, demographic, psychological and social factors were analysed by multivariate regression to determine predictors of exercise capacity (6-min walk distance) and daily activity (daily accelerometer counts). Results: Between 49% and 55% of the variance in 6-min walk distance was explained by variables including New York Heart Association class, depression score, attitude to ageing and use of walking aids. Only 11% to 26% of the variance in accelerometer scores was explained by the model; 6-min walk distance was the only consistent predictor of daily activity. Conclusions: Physical, psychological and attitudinal variables contribute to variance of the 6-min walk. Six-minute walk distance predicts a small amount of the variance in daily activity, but the majority of variance in daily activity remains unexplained and requires further investigation.

KW - Aged

KW - Heart failure

KW - Exercise capacity

KW - Daily activity

KW - Congestive

U2 - 10.1016/j.ejheart.2005.03.008

DO - 10.1016/j.ejheart.2005.03.008

M3 - Article

C2 - 16048742

SN - 1388-9842

VL - 8

SP - 203

EP - 207

JO - European Journal of Heart Failure

JF - European Journal of Heart Failure

IS - 2

ER -