Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease

Rachel E. Harris; Hazel Duncan; Elaine Buchanan; Tracey Cardigan; Vikki Garrick; Lee Curtis; Lisa Gervais; Andrew Barclay; Graham Haddock; Richard Hansen; Rachel Tayler; Gregor Walker; Richard K. Russell

doi:10.1097/MPG.0000000000002595

Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease

Rachel E. Harris, Hazel Duncan, Elaine Buchanan, Tracey Cardigan, Vikki Garrick, Lee Curtis, Lisa Gervais, Andrew Barclay, Graham Haddock, Richard Hansen, Rachel Tayler, Gregor Walker, Richard K. Russell

Molecular and Clinical Medicine

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Exclusive enteral nutrition (EEN) is effective in inducing remission in paediatric Crohn Disease (CD) and has been shown to reduce inflammation and improve outcomes in adult CD patients when used before resectional surgery. This retrospective study demonstrates that preoperative EEN is achievable in paediatric CD patients undergoing right hemicolectomy and is associated with positive peri-operative outcomes. Seventeen patients (8 who received preoperative EEN and 9 who did not) were included in the study. Six of 8 (75.0%) managed EEN orally; 1 via nasogastric tube and another via a previously sited gastrostomy. Use of preoperative EEN was associated with a decreased rate of moderate/severe disease on resection pathology (5/8 [62.5%] vs 9/9 [100%]; P = 0.04). Larger studies are required to determine the wider potential benefits of preoperative EEN on postoperative outcomes within paediatric practice.

Original language	English
Pages (from-to)	503-507
Number of pages	5
Journal	Journal of Pediatric Gastroenterology and Nutrition
Volume	70
Issue number	4
DOIs	https://doi.org/10.1097/MPG.0000000000002595
Publication status	Published - Apr 2020

Keywords

Crohn disease
exclusive enteral nutrition
inflammatory bowel disease
resectional surgery
right hemicolectomy

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Gastroenterology

Access to Document

10.1097/MPG.0000000000002595

Cite this

Harris, R. E., Duncan, H., Buchanan, E., Cardigan, T., Garrick, V., Curtis, L., Gervais, L., Barclay, A., Haddock, G., Hansen, R., Tayler, R., Walker, G., & Russell, R. K. (2020). Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease. Journal of Pediatric Gastroenterology and Nutrition, 70(4), 503-507. https://doi.org/10.1097/MPG.0000000000002595

@article{8d5f338e6eb849bb8010113e112febe3,

title = "Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease",

abstract = "Exclusive enteral nutrition (EEN) is effective in inducing remission in paediatric Crohn Disease (CD) and has been shown to reduce inflammation and improve outcomes in adult CD patients when used before resectional surgery. This retrospective study demonstrates that preoperative EEN is achievable in paediatric CD patients undergoing right hemicolectomy and is associated with positive peri-operative outcomes. Seventeen patients (8 who received preoperative EEN and 9 who did not) were included in the study. Six of 8 (75.0%) managed EEN orally; 1 via nasogastric tube and another via a previously sited gastrostomy. Use of preoperative EEN was associated with a decreased rate of moderate/severe disease on resection pathology (5/8 [62.5%] vs 9/9 [100%]; P = 0.04). Larger studies are required to determine the wider potential benefits of preoperative EEN on postoperative outcomes within paediatric practice.",

keywords = "Crohn disease, exclusive enteral nutrition, inflammatory bowel disease, resectional surgery, right hemicolectomy",

author = "Harris, {Rachel E.} and Hazel Duncan and Elaine Buchanan and Tracey Cardigan and Vikki Garrick and Lee Curtis and Lisa Gervais and Andrew Barclay and Graham Haddock and Richard Hansen and Rachel Tayler and Gregor Walker and Russell, {Richard K.}",

year = "2020",

month = apr,

doi = "10.1097/MPG.0000000000002595",

language = "English",

volume = "70",

pages = "503--507",

journal = "Journal of Pediatric Gastroenterology and Nutrition",

issn = "0277-2116",

publisher = "Lippincott Williams and Wilkins Ltd.",

number = "4",

}

Harris, RE, Duncan, H, Buchanan, E, Cardigan, T, Garrick, V, Curtis, L, Gervais, L, Barclay, A, Haddock, G, Hansen, R, Tayler, R, Walker, G & Russell, RK 2020, 'Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease', Journal of Pediatric Gastroenterology and Nutrition, vol. 70, no. 4, pp. 503-507. https://doi.org/10.1097/MPG.0000000000002595

TY - JOUR

T1 - Prehabilitation

T2 - The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease

AU - Harris, Rachel E.

AU - Duncan, Hazel

AU - Buchanan, Elaine

AU - Cardigan, Tracey

AU - Garrick, Vikki

AU - Curtis, Lee

AU - Gervais, Lisa

AU - Barclay, Andrew

AU - Haddock, Graham

AU - Hansen, Richard

AU - Tayler, Rachel

AU - Walker, Gregor

AU - Russell, Richard K.

PY - 2020/4

Y1 - 2020/4

N2 - Exclusive enteral nutrition (EEN) is effective in inducing remission in paediatric Crohn Disease (CD) and has been shown to reduce inflammation and improve outcomes in adult CD patients when used before resectional surgery. This retrospective study demonstrates that preoperative EEN is achievable in paediatric CD patients undergoing right hemicolectomy and is associated with positive peri-operative outcomes. Seventeen patients (8 who received preoperative EEN and 9 who did not) were included in the study. Six of 8 (75.0%) managed EEN orally; 1 via nasogastric tube and another via a previously sited gastrostomy. Use of preoperative EEN was associated with a decreased rate of moderate/severe disease on resection pathology (5/8 [62.5%] vs 9/9 [100%]; P = 0.04). Larger studies are required to determine the wider potential benefits of preoperative EEN on postoperative outcomes within paediatric practice.

AB - Exclusive enteral nutrition (EEN) is effective in inducing remission in paediatric Crohn Disease (CD) and has been shown to reduce inflammation and improve outcomes in adult CD patients when used before resectional surgery. This retrospective study demonstrates that preoperative EEN is achievable in paediatric CD patients undergoing right hemicolectomy and is associated with positive peri-operative outcomes. Seventeen patients (8 who received preoperative EEN and 9 who did not) were included in the study. Six of 8 (75.0%) managed EEN orally; 1 via nasogastric tube and another via a previously sited gastrostomy. Use of preoperative EEN was associated with a decreased rate of moderate/severe disease on resection pathology (5/8 [62.5%] vs 9/9 [100%]; P = 0.04). Larger studies are required to determine the wider potential benefits of preoperative EEN on postoperative outcomes within paediatric practice.

KW - Crohn disease

KW - exclusive enteral nutrition

KW - inflammatory bowel disease

KW - resectional surgery

KW - right hemicolectomy

UR - http://www.scopus.com/inward/record.url?scp=85082342430&partnerID=8YFLogxK

U2 - 10.1097/MPG.0000000000002595

DO - 10.1097/MPG.0000000000002595

M3 - Article

C2 - 31880668

SN - 0277-2116

VL - 70

SP - 503

EP - 507

JO - Journal of Pediatric Gastroenterology and Nutrition

JF - Journal of Pediatric Gastroenterology and Nutrition

IS - 4

ER -

Prehabilitation: The impact of preoperative exclusive enteral nutrition on paediatric patients with Crohn Disease

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this