Prevalence estimates of diagnosed viral hepatitis B, liver condition outcomes and hospitalization costs: a population record-linkage study in Tayside, Scotland

D.J. McLernon (Lead / Corresponding author), P.T. Donnan, J.F. Dillon

    Research output: Contribution to journalArticle

    Abstract

    We estimated prevalence and incidence of liver condition outcomes, and costs to the health service of diagnosed hepatitis B virus (HBV) in Tayside, UK. HBV patients were identified from electronic virology data between 1989 and 2003. The health resource costs of HBV for surface antigen-positive (HBsAg+) patients and HBV (HBsAg+ or immune, i.e. recovered) patients were calculated. A total of 633 patients had HBV (275 HBsAg+), and were more likely to be male (62% vs. 48%), older (mean age 42·6 vs. 39·2 years) and deprived than the general population. The prevalence of immune individuals increased steadily. Post-HBV diagnosis, 24% of immune and 13% of HBsAg+ patients were diagnosed with a liver condition. The median cost per immune patient (£3023) was greater than per HBsAg+ patient (£1498) (P = 0·02). While increasing prevalence of immune HBV patients highlights an increase in screening and treatment, the costs associated with this group are high.
    Original languageEnglish
    Pages (from-to)2122-2130
    Number of pages9
    JournalEpidemiology and Infection
    Volume141
    Issue number10
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Hepatitis B.
    • EPIDEMIOLOGY
    • DISEASE
    • BURDEN
    • VIRUS

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