Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema

Sara J. Brown; Aileen Sandilands; Yiwei Zhao; Haihui Liao; Caroline L. Relton; Simon J. Meggitt; Richard C. Trembath; Jonathan N. W. N. Barker; Nick J. Reynolds; Heather J. Cordell; W. H. Irwin McLean

doi:10.1038/sj.jid.5701206

Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema

Sara J. Brown, Aileen Sandilands, Yiwei Zhao, Haihui Liao, Caroline L. Relton, Simon J. Meggitt, Richard C. Trembath, Jonathan N. W. N. Barker, Nick J. Reynolds, Heather J. Cordell, W. H. Irwin McLean

Research output: Contribution to journal › Letter › peer-review

91 Citations (Scopus)

Original language	English
Pages (from-to)	1591-1594
Number of pages	5
Journal	Journal of Investigative Dermatology
Volume	128
Issue number	6
Early online date	20 Dec 2007
DOIs	https://doi.org/10.1038/sj.jid.5701206
Publication status	Published - Jun 2008

Keywords

Cause ichthyosis vulgaris
Epidermal differentiation
Rare mutations
Dermatitis
Skin

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Cite this

Brown, S. J., Sandilands, A., Zhao, Y., Liao, H., Relton, C. L., Meggitt, S. J., Trembath, R. C., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., & McLean, W. H. I. (2008). Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema. Journal of Investigative Dermatology, 128(6), 1591-1594. https://doi.org/10.1038/sj.jid.5701206

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title = "Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema",

keywords = "Cause ichthyosis vulgaris, Epidermal differentiation, Rare mutations, Dermatitis, Skin",

author = "Brown, {Sara J.} and Aileen Sandilands and Yiwei Zhao and Haihui Liao and Relton, {Caroline L.} and Meggitt, {Simon J.} and Trembath, {Richard C.} and Barker, {Jonathan N. W. N.} and Reynolds, {Nick J.} and Cordell, {Heather J.} and McLean, {W. H. Irwin}",

year = "2008",

month = jun,

doi = "10.1038/sj.jid.5701206",

language = "English",

volume = "128",

pages = "1591--1594",

journal = "Journal of Investigative Dermatology",

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}

Brown, SJ, Sandilands, A, Zhao, Y, Liao, H, Relton, CL, Meggitt, SJ, Trembath, RC, Barker, JNWN, Reynolds, NJ, Cordell, HJ & McLean, WHI 2008, 'Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema', Journal of Investigative Dermatology, vol. 128, no. 6, pp. 1591-1594. https://doi.org/10.1038/sj.jid.5701206

TY - JOUR

T1 - Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema

AU - Brown, Sara J.

AU - Sandilands, Aileen

AU - Zhao, Yiwei

AU - Liao, Haihui

AU - Relton, Caroline L.

AU - Meggitt, Simon J.

AU - Trembath, Richard C.

AU - Barker, Jonathan N. W. N.

AU - Reynolds, Nick J.

AU - Cordell, Heather J.

AU - McLean, W. H. Irwin

PY - 2008/6

Y1 - 2008/6

KW - Cause ichthyosis vulgaris

KW - Epidermal differentiation

KW - Rare mutations

KW - Dermatitis

KW - Skin

U2 - 10.1038/sj.jid.5701206

DO - 10.1038/sj.jid.5701206

M3 - Letter

SN - 0022-202X

VL - 128

SP - 1591

EP - 1594

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 6

ER -