Prevalent and low-frequency null mutations in the filaggrin gene are associated with early-onset and persistent atopic eczema

Sara J. Brown, Aileen Sandilands, Yiwei Zhao, Haihui Liao, Caroline L. Relton, Simon J. Meggitt, Richard C. Trembath, Jonathan N. W. N. Barker, Nick J. Reynolds, Heather J. Cordell, W. H. Irwin McLean

    Research output: Contribution to journalLetter

    77 Citations (Scopus)
    Original languageEnglish
    Pages (from-to)1591-1594
    Number of pages5
    JournalJournal of Investigative Dermatology
    Volume128
    Issue number6
    Early online date20 Dec 2007
    DOIs
    Publication statusPublished - Jun 2008

    Keywords

    • Cause ichthyosis vulgaris
    • Epidermal differentiation
    • Rare mutations
    • Dermatitis
    • Skin

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