Prevention/treatment of ichthyosis vulgaris, atopy and other disorders

William Henry Irwin McLean; Frances Jan Dorothy Smith

Prevention/treatment of ichthyosis vulgaris, atopy and other disorders

William Henry Irwin McLean (Inventor), Frances Jan Dorothy Smith (Inventor)

Research output: Patent

Abstract

The present invention relates to the prevention/treatment of ichthyosis vulgaris (IV), atopy and potentially other disorders associated with loss-of-function mutations in the filaggrin gene sequence. The prevention/therapy is based on the use of agents which enable the host's translational machinery to read through a nonsense mutation found in a mutant allele of the filaggrin gene.

Original language	English
Patent number	WO/2007/083094
IPC	C07K 14/47 (2006.01), A61K 31/7036 (2006.01), A61K 48/00 (2006.01), C12Q 1/68 (2006.01)
Publication status	Published - 26 Jul 2007

Access to Document

http://patentscope.wipo.int/search/en/detail.jsf?docId=WO2007083094&recNum=1&maxRec=2&office=&prevFilter=&sortOption=Pub+Date+Desc&queryString=FP%3Afilaggrin+AND+PA%3Amclean+&tab=PCT+Biblio

Cite this

@misc{6e2a149ac9044a8aa4e05615d3c426da,

title = "Prevention/treatment of ichthyosis vulgaris, atopy and other disorders",

abstract = "The present invention relates to the prevention/treatment of ichthyosis vulgaris (IV), atopy and potentially other disorders associated with loss-of-function mutations in the filaggrin gene sequence. The prevention/therapy is based on the use of agents which enable the host's translational machinery to read through a nonsense mutation found in a mutant allele of the filaggrin gene.",

author = "McLean, {William Henry Irwin} and Smith, {Frances Jan Dorothy}",

year = "2007",

month = jul,

day = "26",

language = "English",

type = "Patent",

note = "WO/2007/083094; C07K 14/47 (2006.01), A61K 31/7036 (2006.01), A61K 48/00 (2006.01), C12Q 1/68 (2006.01) ",

}

TY - PAT

T1 - Prevention/treatment of ichthyosis vulgaris, atopy and other disorders

AU - McLean, William Henry Irwin

AU - Smith, Frances Jan Dorothy

PY - 2007/7/26

Y1 - 2007/7/26

N2 - The present invention relates to the prevention/treatment of ichthyosis vulgaris (IV), atopy and potentially other disorders associated with loss-of-function mutations in the filaggrin gene sequence. The prevention/therapy is based on the use of agents which enable the host's translational machinery to read through a nonsense mutation found in a mutant allele of the filaggrin gene.

AB - The present invention relates to the prevention/treatment of ichthyosis vulgaris (IV), atopy and potentially other disorders associated with loss-of-function mutations in the filaggrin gene sequence. The prevention/therapy is based on the use of agents which enable the host's translational machinery to read through a nonsense mutation found in a mutant allele of the filaggrin gene.

M3 - Patent

M1 - WO/2007/083094

ER -

Prevention/treatment of ichthyosis vulgaris, atopy and other disorders

Abstract

Access to Document

Fingerprint

Cite this