Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol

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    Abstract

    High doses of inhaled albuterol produce substantial improvements in bronchodilatation but are associated with dose-related systemic side effects including hypokalemia and hypomagnesemia. Concomitant diuretic therapy also produces these metabolic sequelae and may therefore precipitate cardiac arrhythmias in patients taking this combination of drugs. The purpose of this study was to investigate the electrocardiographic (ECG) effects of high-dose inhaled albuterol, and to evaluate whether potentiation occurs with bendrofluazide.
    Original languageEnglish
    Pages (from-to)653-657
    Number of pages5
    JournalAmerican Journal of Medicine
    Volume86
    Issue number6
    DOIs
    Publication statusPublished - 1989

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