Prognostic significance and measurement of exercise-derived hemodynamic variables in patients with heart failure

Chim C. Lang, Piergiuseppe Agostoni, Donna M. Mancini

    Research output: Contribution to journalReview article

    53 Citations (Scopus)

    Abstract

    The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2 Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.

    Original languageEnglish
    Pages (from-to)672-679
    Number of pages8
    JournalJournal of Cardiac Failure
    Volume13
    Issue number8
    DOIs
    Publication statusPublished - Oct 2007

    Keywords

    • chronic heart failure
    • cardiac transplantation
    • exercise
    • cardiac output
    • PEAK OXYGEN-CONSUMPTION
    • GAS REBREATHING TECHNIQUE
    • CARDIAC PUMPING CAPACITY
    • CORONARY-ARTERY-DISEASE
    • NONINVASIVE MEASUREMENT
    • IMPEDANCE CARDIOGRAPHY
    • AMBULATORY PATIENTS
    • STROKE VOLUME
    • DILATED CARDIOMYOPATHY
    • RISK STRATIFICATION

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