Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak)

C L Barratt (Lead / Corresponding author), I D McLeod, B C Dunphy, I D Cooke

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.

Original languageEnglish
Pages (from-to)1240-4
Number of pages5
JournalHuman Reproduction
Volume7
Issue number9
DOIs
Publication statusPublished - 1 Oct 1992

Keywords

  • Adult
  • Cervix Mucus
  • Female
  • Follow-Up Studies
  • Humans
  • Infertility, Male/diagnosis
  • Life Tables
  • Male
  • Middle Aged
  • Osmosis
  • Predictive Value of Tests
  • Pregnancy
  • Prospective Studies
  • Regression Analysis
  • Sperm Count
  • Sperm Motility
  • Spermatozoa/physiology

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