Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak)

C L Barratt; I D McLeod; B C Dunphy; I D Cooke

doi:10.1093/oxfordjournals.humrep.a137834

Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak)

C L Barratt (Lead / Corresponding author), I D McLeod, B C Dunphy, I D Cooke

Undergraduate Medicine

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.

Original language	English
Pages (from-to)	1240-4
Number of pages	5
Journal	Human Reproduction
Volume	7
Issue number	9
DOIs	https://doi.org/10.1093/oxfordjournals.humrep.a137834
Publication status	Published - 1 Oct 1992

Keywords

Adult
Cervix Mucus
Female
Follow-Up Studies
Humans
Infertility, Male/diagnosis
Life Tables
Male
Middle Aged
Osmosis
Predictive Value of Tests
Pregnancy
Prospective Studies
Regression Analysis
Sperm Count
Sperm Motility
Spermatozoa/physiology

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Cite this

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title = "Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak)",

abstract = "The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.",

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T1 - Prognostic value of two putative sperm function tests

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AU - Dunphy, B C

AU - Cooke, I D

PY - 1992/10/1

Y1 - 1992/10/1

N2 - The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.

AB - The clinical value of two inexpensive and easy to perform sperm function tests (hypo-osmotic swelling and bovine sperm mucus penetration tests) were examined in a prospective study of in-vivo conception rates in 325 couples. Both tests were of no significant value alone or in combination with traditional semen characteristics in predicting pregnancy outcome. The two most predictive factors of conception were the length of infertility and percentage of progressively motile spermatozoa. Our data support the further investigation of sperm function using more sophisticated quantitative tests, specifically the examination of sperm motility.

KW - Adult

KW - Cervix Mucus

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Infertility, Male/diagnosis

KW - Life Tables

KW - Male

KW - Middle Aged

KW - Osmosis

KW - Predictive Value of Tests

KW - Pregnancy

KW - Prospective Studies

KW - Regression Analysis

KW - Sperm Count

KW - Sperm Motility

KW - Spermatozoa/physiology

U2 - 10.1093/oxfordjournals.humrep.a137834

DO - 10.1093/oxfordjournals.humrep.a137834

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C2 - 1479005

SN - 0268-1161

VL - 7

SP - 1240

EP - 1244

JO - Human Reproduction

JF - Human Reproduction

IS - 9

ER -

Prognostic value of two putative sperm function tests: hypo-osmotic swelling and bovine sperm mucus penetration test (Penetrak)

Abstract

Keywords

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