Abstract
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family. New techniques that apply machine learning and discriminant analysis show promise as alternatives to neural networks.
Original language | English |
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Pages (from-to) | 372-376 |
Number of pages | 5 |
Journal | Current Opinion in Structural Biology |
Volume | 5 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jun 1995 |
Keywords
- Animals
- Humans
- Predictive value of tests
- Protein structure, Secondary
- Proteins
- Sequence alignment
- Sequence analysis