Protein sequence alignment techniques

Geoffrey J. Barton (Lead / Corresponding author)

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The basic algorithms for alignment of two or more protein sequences are explained. Alternative methods for scoring substitutions and gaps (insertions and deletions) are described, as are global and local alignment methods. Multiple alignment techniques are explained, including methods for profile comparison. A summary is given of programs for the alignment and analysis of protein sequences, either from sequence alone, or from three-dimensional structure.

Original languageEnglish
Pages (from-to)1139-1146
Number of pages8
JournalActa Crystallographica Section D: Biological Crystallography
Volume54
Issue number6, no. 1
DOIs
Publication statusPublished - 1 Nov 1998

Keywords

  • Algorithms
  • Protein conformation
  • Sequence alignment

Fingerprint Dive into the research topics of 'Protein sequence alignment techniques'. Together they form a unique fingerprint.

  • Cite this