PtdIns(4,5)P₂-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism

Biochemistry, Genetics and Molecular Biology

• Signal Transduction 100%
• Enzymatic Hydrolysis 100%
• Phosphatase 100%
• Cell Function 50%
• Cell Membrane 50%
• Phosphoinositide 3-Kinase 50%
• Tumor Suppressor Protein 50%
• Lipid 50%
• Integral Membrane Protein 50%
• Tensin 50%
• Chromosome 10 50%
• Phosphatidylinositol 4,5-bisphosphate 50%
• Peripheral Membrane Protein 50%
• Inositol Trisphosphate 50%
• Lipid Bilayer 50%
• Phospholipid Membrane 50%
• Lecithinase 50%
• Diglyceride 50%

Keyphrases

• Cell Signaling 100%
• PtdIns(4,5)P2 100%
• Regulatory Mechanism 100%
• PtdIns(3,4,5)P3 33%
• Membrane Protein 33%
• Cell Behavior 16%
• Phosphoinositide 3-kinase (PI3K) 16%
• Phosphorylation 16%
• Protein Binding 16%
• Phosphatase 16%
• Tumor Suppressor 16%
• Molecular Dynamics Simulation 16%
• Integral Membrane Protein 16%
• Membrane Binding 16%
• Phosphatase Activity 16%
• Tensin Homolog 16%
• Plasma Membrane 16%
• Phospholipase C 16%
• Chromosome 10 16%
• Hydrolysis 16%
• Structural Information 16%
• Diacylglycerol 16%
• Phosphatidylinositol 4,5-bisphosphate (PIP2) 16%
• Multiple Mechanisms 16%
• Peripheral Membrane Protein 16%
• Structural Determination 16%
• Lipid Bilayer 16%
• PTEN Regulation 16%
• Pathological Process 16%
• Inositol Trisphosphate 16%
• Anionic Lipids 16%
• Phospholipid Membrane 16%
• Neutron Reflectivity 16%