Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

William Farnaby, Manfred Koegl, Michael J. Roy, Claire Whitworth, Emelyne Diers, Nicole Trainor, David Zollman, Steffen Steurer, Jale Karolyi-oezguer, Carina Riedmueller, Teresa Gmaschitz, Johannes Wachter, Christian Dank, Michael Galant, Bernadette Sharps, Klaus Rumpel, Elisabeth Traxler, Thomas Gerstberger, Renate Schnitzer, Oliver PetermannPeter Greb, Harald Weinstabl, Gerd Bader, Andreas Zoephel, Alexander Weiss-Puxbaum, Katharina Ehrenhöfer-Wölfer, Simon Wöhrle, Guido Boehmelt, Joerg Rinnenthal, Heribert Arnhof, Nicola Wiechens, Meng-Ying Wu, Tom Owen-Hughes, Peter Ettmayer, Mark Pearson, Darryl B. Mcconnell, Alessio Ciulli

Research output: Contribution to journalArticle

Abstract

Correction to: Nature Chemical Biology, https://doi.org/10.1038/s41589-019-0294-6, published online 10 June 2019

In the version of this article originally published, several lines of text in the last paragraph of the right column on page 1 of the PDF were transposed into the bottom paragraph of the left column. The affected text of the left column should read “The ATP-dependent activities of the BAF (SWI/SNF) chromatin remodeling complexes affect the positioning of nucleosomes on DNA and thereby many cellular processes related to chromatin structure, including transcription, DNA repair and decatenation of chromosomes during mitosis12,13.” The affected text of the right column should read “SMARCA2/4BD inhibitors are thus precluded from use for the treatment of SMARCA4 mutant cancers but could provide attractive ligands for PROTAC conjugation. Small molecules binding to other bromodomains have been successfully converted into PROTACs by conjugating them with structures capable of binding to the E3 ligases von Hippel−Lindau (VHL) or cereblon5,6,10,11,25,26,27.” The errors have been corrected in the PDF version of the paper.
Original languageEnglish
Pages (from-to)846
Number of pages1
JournalNature Chemical Biology
Volume15
Issue number8
DOIs
Publication statusPublished - 2 Jul 2019

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Chromatin Assembly and Disassembly
Ubiquitin-Protein Ligases
Nucleosomes
DNA Repair
Chromatin
Chromosomes
Adenosine Triphosphate
Ligands
DNA
Neoplasms

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Farnaby, William ; Koegl, Manfred ; Roy, Michael J. ; Whitworth, Claire ; Diers, Emelyne ; Trainor, Nicole ; Zollman, David ; Steurer, Steffen ; Karolyi-oezguer, Jale ; Riedmueller, Carina ; Gmaschitz, Teresa ; Wachter, Johannes ; Dank, Christian ; Galant, Michael ; Sharps, Bernadette ; Rumpel, Klaus ; Traxler, Elisabeth ; Gerstberger, Thomas ; Schnitzer, Renate ; Petermann, Oliver ; Greb, Peter ; Weinstabl, Harald ; Bader, Gerd ; Zoephel, Andreas ; Weiss-Puxbaum, Alexander ; Ehrenhöfer-Wölfer, Katharina ; Wöhrle, Simon ; Boehmelt, Guido ; Rinnenthal, Joerg ; Arnhof, Heribert ; Wiechens, Nicola ; Wu, Meng-Ying ; Owen-Hughes, Tom ; Ettmayer, Peter ; Pearson, Mark ; Mcconnell, Darryl B. ; Ciulli, Alessio. / Publisher Correction : BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. In: Nature Chemical Biology. 2019 ; Vol. 15, No. 8. pp. 846.
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title = "Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design",
abstract = "Correction to: Nature Chemical Biology, https://doi.org/10.1038/s41589-019-0294-6, published online 10 June 2019In the version of this article originally published, several lines of text in the last paragraph of the right column on page 1 of the PDF were transposed into the bottom paragraph of the left column. The affected text of the left column should read “The ATP-dependent activities of the BAF (SWI/SNF) chromatin remodeling complexes affect the positioning of nucleosomes on DNA and thereby many cellular processes related to chromatin structure, including transcription, DNA repair and decatenation of chromosomes during mitosis12,13.” The affected text of the right column should read “SMARCA2/4BD inhibitors are thus precluded from use for the treatment of SMARCA4 mutant cancers but could provide attractive ligands for PROTAC conjugation. Small molecules binding to other bromodomains have been successfully converted into PROTACs by conjugating them with structures capable of binding to the E3 ligases von Hippel−Lindau (VHL) or cereblon5,6,10,11,25,26,27.” The errors have been corrected in the PDF version of the paper.",
author = "William Farnaby and Manfred Koegl and Roy, {Michael J.} and Claire Whitworth and Emelyne Diers and Nicole Trainor and David Zollman and Steffen Steurer and Jale Karolyi-oezguer and Carina Riedmueller and Teresa Gmaschitz and Johannes Wachter and Christian Dank and Michael Galant and Bernadette Sharps and Klaus Rumpel and Elisabeth Traxler and Thomas Gerstberger and Renate Schnitzer and Oliver Petermann and Peter Greb and Harald Weinstabl and Gerd Bader and Andreas Zoephel and Alexander Weiss-Puxbaum and Katharina Ehrenh{\"o}fer-W{\"o}lfer and Simon W{\"o}hrle and Guido Boehmelt and Joerg Rinnenthal and Heribert Arnhof and Nicola Wiechens and Meng-Ying Wu and Tom Owen-Hughes and Peter Ettmayer and Mark Pearson and Mcconnell, {Darryl B.} and Alessio Ciulli",
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Farnaby, W, Koegl, M, Roy, MJ, Whitworth, C, Diers, E, Trainor, N, Zollman, D, Steurer, S, Karolyi-oezguer, J, Riedmueller, C, Gmaschitz, T, Wachter, J, Dank, C, Galant, M, Sharps, B, Rumpel, K, Traxler, E, Gerstberger, T, Schnitzer, R, Petermann, O, Greb, P, Weinstabl, H, Bader, G, Zoephel, A, Weiss-Puxbaum, A, Ehrenhöfer-Wölfer, K, Wöhrle, S, Boehmelt, G, Rinnenthal, J, Arnhof, H, Wiechens, N, Wu, M-Y, Owen-Hughes, T, Ettmayer, P, Pearson, M, Mcconnell, DB & Ciulli, A 2019, 'Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design', Nature Chemical Biology, vol. 15, no. 8, pp. 846. https://doi.org/10.1038/s41589-019-0329-z

Publisher Correction : BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. / Farnaby, William; Koegl, Manfred; Roy, Michael J.; Whitworth, Claire; Diers, Emelyne; Trainor, Nicole; Zollman, David; Steurer, Steffen; Karolyi-oezguer, Jale; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Galant, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Gerstberger, Thomas; Schnitzer, Renate; Petermann, Oliver; Greb, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Ehrenhöfer-Wölfer, Katharina; Wöhrle, Simon; Boehmelt, Guido; Rinnenthal, Joerg; Arnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; Mcconnell, Darryl B.; Ciulli, Alessio (Lead / Corresponding author).

In: Nature Chemical Biology, Vol. 15, No. 8, 02.07.2019, p. 846.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Publisher Correction

T2 - BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

AU - Farnaby, William

AU - Koegl, Manfred

AU - Roy, Michael J.

AU - Whitworth, Claire

AU - Diers, Emelyne

AU - Trainor, Nicole

AU - Zollman, David

AU - Steurer, Steffen

AU - Karolyi-oezguer, Jale

AU - Riedmueller, Carina

AU - Gmaschitz, Teresa

AU - Wachter, Johannes

AU - Dank, Christian

AU - Galant, Michael

AU - Sharps, Bernadette

AU - Rumpel, Klaus

AU - Traxler, Elisabeth

AU - Gerstberger, Thomas

AU - Schnitzer, Renate

AU - Petermann, Oliver

AU - Greb, Peter

AU - Weinstabl, Harald

AU - Bader, Gerd

AU - Zoephel, Andreas

AU - Weiss-Puxbaum, Alexander

AU - Ehrenhöfer-Wölfer, Katharina

AU - Wöhrle, Simon

AU - Boehmelt, Guido

AU - Rinnenthal, Joerg

AU - Arnhof, Heribert

AU - Wiechens, Nicola

AU - Wu, Meng-Ying

AU - Owen-Hughes, Tom

AU - Ettmayer, Peter

AU - Pearson, Mark

AU - Mcconnell, Darryl B.

AU - Ciulli, Alessio

PY - 2019/7/2

Y1 - 2019/7/2

N2 - Correction to: Nature Chemical Biology, https://doi.org/10.1038/s41589-019-0294-6, published online 10 June 2019In the version of this article originally published, several lines of text in the last paragraph of the right column on page 1 of the PDF were transposed into the bottom paragraph of the left column. The affected text of the left column should read “The ATP-dependent activities of the BAF (SWI/SNF) chromatin remodeling complexes affect the positioning of nucleosomes on DNA and thereby many cellular processes related to chromatin structure, including transcription, DNA repair and decatenation of chromosomes during mitosis12,13.” The affected text of the right column should read “SMARCA2/4BD inhibitors are thus precluded from use for the treatment of SMARCA4 mutant cancers but could provide attractive ligands for PROTAC conjugation. Small molecules binding to other bromodomains have been successfully converted into PROTACs by conjugating them with structures capable of binding to the E3 ligases von Hippel−Lindau (VHL) or cereblon5,6,10,11,25,26,27.” The errors have been corrected in the PDF version of the paper.

AB - Correction to: Nature Chemical Biology, https://doi.org/10.1038/s41589-019-0294-6, published online 10 June 2019In the version of this article originally published, several lines of text in the last paragraph of the right column on page 1 of the PDF were transposed into the bottom paragraph of the left column. The affected text of the left column should read “The ATP-dependent activities of the BAF (SWI/SNF) chromatin remodeling complexes affect the positioning of nucleosomes on DNA and thereby many cellular processes related to chromatin structure, including transcription, DNA repair and decatenation of chromosomes during mitosis12,13.” The affected text of the right column should read “SMARCA2/4BD inhibitors are thus precluded from use for the treatment of SMARCA4 mutant cancers but could provide attractive ligands for PROTAC conjugation. Small molecules binding to other bromodomains have been successfully converted into PROTACs by conjugating them with structures capable of binding to the E3 ligases von Hippel−Lindau (VHL) or cereblon5,6,10,11,25,26,27.” The errors have been corrected in the PDF version of the paper.

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DO - 10.1038/s41589-019-0329-z

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VL - 15

SP - 846

JO - Nature Chemical Biology

JF - Nature Chemical Biology

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