Pulse wave analysis and pulse wave velocity: a critical review of their strengths and weaknesses

Justine Ina Davies, Allan D. Struthers

    Research output: Contribution to journalArticlepeer-review

    210 Citations (Scopus)

    Abstract

    The study of the pulse using the technique of applanation tonometry is undergoing a resurgence with the development of new computerized equipment. We aim here to present a critical review of the uses, potential uses, strengths and weaknesses of the technique of applanation tonometry for the assessment of augmentation index and pulse wave velocity. We will review the technique of applanation tonometry, the physiological factors affecting pulse wave velocity and pulse wave analysis, the changes in pulse wave velocity and pulse wave analysis with pharmacological interventions, and the use of the technique of applanation tonometry as a prognostic tool. We conclude that, although the technique of applanation tonometry initially seems promising, several pertinent issues need to be addressed before it can be used reliably as a clinical or research tool. Importantly, use of the technique of applanation tonometry to derive the central waveform from non-invasively acquired peripheral data needs to be validated prospectively.
    Original languageEnglish
    Pages (from-to)463-72
    Number of pages10
    JournalJournal of Hypertension
    Volume21
    Issue number3
    DOIs
    Publication statusPublished - Mar 2003

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