Quantitative effects of short- and long-term vasectomy on mouse spermatogenesis and sperm transport

C L Barratt, J Cohen

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

To date, there are no comprehensive quantitative studies detailing the effect of vasectomy on the mouse testes. We examined the effects of vasectomy on testicular germ cell numbers using detailed light microscopy, and the effect of long-term vasectomy on sperm transport to the caput epididymis using radiolabelled germ cells. Short-term vasectomy has no significant effects on the number of germ cells within the testes; however, after long-term vasectomy, spermiogenesis was affected. Surprisingly, even after long-term vasectomy, the rate of spermatogenesis and sperm transport to the epididymis was unaffected.

Original languageEnglish
Pages (from-to)415-24
Number of pages10
JournalContraception
Volume37
Issue number4
DOIs
Publication statusPublished - Apr 1988

Fingerprint

Sperm Transport
Vasectomy
Spermatogenesis
Germ Cells
Epididymis
Testis
Microscopy
Cell Count
Light

Keywords

  • Animals
  • Epididymis/cytology
  • Male
  • Mice
  • Seminiferous Epithelium/anatomy & histology
  • Seminiferous Tubules/anatomy & histology
  • Sperm Transport
  • Spermatogenesis
  • Testis/cytology
  • Vasectomy

Cite this

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abstract = "To date, there are no comprehensive quantitative studies detailing the effect of vasectomy on the mouse testes. We examined the effects of vasectomy on testicular germ cell numbers using detailed light microscopy, and the effect of long-term vasectomy on sperm transport to the caput epididymis using radiolabelled germ cells. Short-term vasectomy has no significant effects on the number of germ cells within the testes; however, after long-term vasectomy, spermiogenesis was affected. Surprisingly, even after long-term vasectomy, the rate of spermatogenesis and sperm transport to the epididymis was unaffected.",
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Quantitative effects of short- and long-term vasectomy on mouse spermatogenesis and sperm transport. / Barratt, C L; Cohen, J.

In: Contraception, Vol. 37, No. 4, 04.1988, p. 415-24.

Research output: Contribution to journalArticle

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