Quantitative sequencing confirms VSG diversity as central to immune evasion by Trypanosoma brucei

Richard McCulloch, Mark C. Field (Lead / Corresponding author)

    Research output: Contribution to journalArticle

    12 Citations (Scopus)

    Abstract

    Antigenic variation is central to the virulence of African trypanosomes, where the VSG coat is used to evade the host immune system. Recent advances in technology have now allowed more secrets of this system to emerge, with the surprising insight that a broad repertoire of VSGs is rapidly expressed. This has major implications for how the parasite must evade the host immune response.

    Original languageEnglish
    Pages (from-to)346-349
    Number of pages4
    JournalTrends in Parasitology
    Volume31
    Issue number8
    Early online date18 May 2015
    DOIs
    Publication statusPublished - Aug 2015

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