Quantum dot superluminescent diodes for optical coherence tomography: Skin imaging

Nikola Krstajić, Louise E. Smith, Stephen John Matcher, David T D Childs, Marco Bonesi, Purnima Daisy Lydia Greenwood, Maxime Hugues, Kenneth Kennedy, Mark Hopkinson, Kristian Michael Groom, Sheila MacNeil, Richard A. Hogg, Rod Smallwood

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    Abstract

    We present a high-power (18 mW continuous wave exiting a single-mode fiber and 35 mW exiting the facet), broadband (85 nm full-width at half-maximum) quantum dot-based superluminescent diode, and apply it to a time-domain optical coherence tomography (OCT) setup. First, we test its performance with increasing optical feedback. Then we demonstrate its imaging properties on tissue-engineered (TE) skin and in vivo skin. OCT allows the tracking of epidermal development in TE skin, while the higher power source allows better sensitivity and depth penetration for imaging of in vivo skin layers.

    Original languageEnglish
    Article number5398870
    Pages (from-to)748-754
    Number of pages7
    JournalIEEE Journal on Selected Topics in Quantum Electronics
    Volume16
    Issue number4
    DOIs
    Publication statusPublished - Jul 2010

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    Keywords

    • Optical coherence tomography (OCT)
    • skin imaging
    • superluminescent diodes
    • tissue engineering

    Cite this

    Krstajić, N., Smith, L. E., Matcher, S. J., Childs, D. T. D., Bonesi, M., Greenwood, P. D. L., Hugues, M., Kennedy, K., Hopkinson, M., Groom, K. M., MacNeil, S., Hogg, R. A., & Smallwood, R. (2010). Quantum dot superluminescent diodes for optical coherence tomography: Skin imaging. IEEE Journal on Selected Topics in Quantum Electronics, 16(4), 748-754. [5398870]. https://doi.org/10.1109/JSTQE.2009.2038597