Quasi-steady state assumptions for non-isolated enzyme-catalyzed reactions

I. Stoleriu, F. A. Davidson, J. L. Liu

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    The nature and validity of the mathematical formulation of Michaelis-Menten type kinetics for enzyme-catalysed biochemical reactions is studied. Almost all previous work has concentrated on isolated reactions, i.e. those without input or other environmental influences. In this paper, we investigate the effects of substrate input on this formulation, in particular, on the nature and validity of the quasi-steady state assumptions.
    Original languageEnglish
    Pages (from-to)82-104
    Number of pages23
    JournalJournal of Mathematical Biology
    Volume48
    Issue number1
    DOIs
    Publication statusPublished - Jan 2004

    Keywords

    • Michaelis-Menten
    • Quasi-steady state
    • Open system

    Fingerprint Dive into the research topics of 'Quasi-steady state assumptions for non-isolated enzyme-catalyzed reactions'. Together they form a unique fingerprint.

    Cite this