Rapid 3D human ribcage and kidney modeling for transcostal HIFU surgery

TY - GEN

T1 - Rapid 3D human ribcage and kidney modeling for transcostal HIFU surgery

AU - Cao, Rui

AU - Gao, Jing

AU - Melzer, Andreas

AU - Nabi, Ghulam

AU - Huang, Zhihong

PY - 2012

Y1 - 2012

N2 - A rapid modeling technique for constructing human ribcage and kidney models for high intensity focused ultrasound through the ribcage is proposed and tested. In this study, a 3D model reconstructed from a patient's CT images provides solutions for the conversion of 3D image data into multi-part volumetric models of kidney and ribcage. The model was imported into PZFlex for simulation of acoustic field analysis. Tissue mimicking materials for the phantom were selected based on the acoustic characterisation result. The effect of the ribcage on HIFU sonication and acoustic pressure distribution were measured in the focal plane. Porcine ribcage sample was used in experiments for comparison. Results showed that with the presence of the ribcage phantom, the maximum temperature at the focus was reduced by approximately 60-70% and the maximum pressure at the focal zone was halved. Focus splitting with the ribcage in place was demonstrated both in experiments and simulations. The development of this model provides basis for using patient's data for transcostal HIFU research and maximise the efficiency of the HIFU surgery.

AB - A rapid modeling technique for constructing human ribcage and kidney models for high intensity focused ultrasound through the ribcage is proposed and tested. In this study, a 3D model reconstructed from a patient's CT images provides solutions for the conversion of 3D image data into multi-part volumetric models of kidney and ribcage. The model was imported into PZFlex for simulation of acoustic field analysis. Tissue mimicking materials for the phantom were selected based on the acoustic characterisation result. The effect of the ribcage on HIFU sonication and acoustic pressure distribution were measured in the focal plane. Porcine ribcage sample was used in experiments for comparison. Results showed that with the presence of the ribcage phantom, the maximum temperature at the focus was reduced by approximately 60-70% and the maximum pressure at the focal zone was halved. Focus splitting with the ribcage in place was demonstrated both in experiments and simulations. The development of this model provides basis for using patient's data for transcostal HIFU research and maximise the efficiency of the HIFU surgery.

KW - 3D model reconstruction

KW - FEASIBILITY

KW - INTENSITY-FOCUSED ULTRASOUND

KW - TMMs

KW - HIFU

KW - transcostal

U2 - 10.1063/1.4769924

DO - 10.1063/1.4769924

M3 - Conference contribution

SN - 9780735411203

T3 - AIP conference proceedings

SP - 95

EP - 100

BT - 12th International Symposium on Therapeutic Ultrasound

A2 - Meairs, Stephen

PB - American Institute of Physics

CY - Melville

T2 - 12th International Society for Therapeutic Ultrasound Symposium

Y2 - 10 June 2012 through 13 June 2012

ER -