Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Karen A Hunt; Deborah J Smyth; Tobias Balschun; Maria Ban; Vanisha Mistry; Tariq Ahmad; Vidya Anand; Jeffrey C Barrett; Leena Bhaw-Rosun; Nicholas A Bockett; Oliver J Brand; Elisabeth Brouwer; Patrick Concannon; Jason D Cooper; Kerith-Rae M Dias; Cleo C van Diemen; Patrick C Dubois; Sarah Edkins; Regina Fölster-Holst; Karin Fransen; David N Glass; Graham A R Heap; Sylvia Hofmann; Tom W J Huizinga; Sarah Hunt; Cordelia Langford; James Lee; John Mansfield; Maria Giovanna Marrosu; Christopher G Mathew; Charles A Mein; Joachim Müller-Quernheim; Sarah Nutland; Suna Onengut-Gumuscu; Willem Ouwehand; Kerra Pearce; Natalie J Prescott; Marcel D Posthumus; Simon Potter; Giulio Rosati; Jennifer Sambrook; Jack Satsangi; Stefan Schreiber; Corina Shtir; Matthew J Simmonds; Marc Sudman; Susan D Thompson; Rene Toes; Gosia Trynka; Timothy J Vyse; Neil M Walker; Stephan Weidinger; Alexandra Zhernakova; Magdalena Zoledziewska; Wellcome Trust Case Control Consortium; Rinse K Weersma; Stephen C L Gough; Stephen Sawcer; Cisca Wijmenga; Miles Parkes; Francesco Cucca; Andre Franke; Panos Deloukas; Stephen S Rich; John A Todd; David A van Heel; Craig Mowat

doi:10.1038/ng.1037

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

Karen A Hunt, Deborah J Smyth, Tobias Balschun, Maria Ban, Vanisha Mistry, Tariq Ahmad, Vidya Anand, Jeffrey C Barrett, Leena Bhaw-Rosun, Nicholas A Bockett, Oliver J Brand, Elisabeth Brouwer, Patrick Concannon, Jason D Cooper, Kerith-Rae M Dias, Cleo C van Diemen, Patrick C Dubois, Sarah Edkins, Regina Fölster-Holst, Karin FransenDavid N Glass, Graham A R Heap, Sylvia Hofmann, Tom W J Huizinga, Sarah Hunt, Cordelia Langford, James Lee, John Mansfield, Maria Giovanna Marrosu, Christopher G Mathew, Charles A Mein, Joachim Müller-Quernheim, Sarah Nutland, Suna Onengut-Gumuscu, Willem Ouwehand, Kerra Pearce, Natalie J Prescott, Marcel D Posthumus, Simon Potter, Giulio Rosati, Jennifer Sambrook, Jack Satsangi, Stefan Schreiber, Corina Shtir, Matthew J Simmonds, Marc Sudman, Susan D Thompson, Rene Toes, Gosia Trynka, Timothy J Vyse, Neil M Walker, Stephan Weidinger, Alexandra Zhernakova, Magdalena Zoledziewska, , , Wellcome Trust Case Control Consortium, Rinse K Weersma, Stephen C L Gough, Stephen Sawcer, Cisca Wijmenga, Miles Parkes, Francesco Cucca, Andre Franke, Panos Deloukas, Stephen S Rich, John A Todd, David A van Heel (Lead / Corresponding author), Craig Mowat (Contributing member)

Research output: Contribution to journal › Letter › peer-review

37 Citations (Scopus)

Original language	English
Pages (from-to)	3-5
Number of pages	3
Journal	Nature Genetics
Volume	44
Issue number	1
DOIs	https://doi.org/10.1038/ng.1037
Publication status	Published - 27 Dec 2011

Keywords

Acetylesterase/genetics
Autoimmune Diseases/genetics
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Variation
Humans
Risk Factors
White People

Access to Document

10.1038/ng.1037

Cite this

Hunt, K. A., Smyth, D. J., Balschun, T., Ban, M., Mistry, V., Ahmad, T., Anand, V., Barrett, J. C., Bhaw-Rosun, L., Bockett, N. A., Brand, O. J., Brouwer, E., Concannon, P., Cooper, J. D., Dias, K.-R. M., van Diemen, C. C., Dubois, P. C., Edkins, S., Fölster-Holst, R., ... Mowat, C. (2011). Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nature Genetics, 44(1), 3-5. https://doi.org/10.1038/ng.1037

@article{d0e49d619aee4dd7a9bb10be8dc41de6,

title = "Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry",

keywords = "Acetylesterase/genetics, Autoimmune Diseases/genetics, Gene Frequency, Genetic Association Studies, Genetic Predisposition to Disease, Genetic Variation, Humans, Risk Factors, White People",

author = "Hunt, {Karen A} and Smyth, {Deborah J} and Tobias Balschun and Maria Ban and Vanisha Mistry and Tariq Ahmad and Vidya Anand and Barrett, {Jeffrey C} and Leena Bhaw-Rosun and Bockett, {Nicholas A} and Brand, {Oliver J} and Elisabeth Brouwer and Patrick Concannon and Cooper, {Jason D} and Dias, {Kerith-Rae M} and {van Diemen}, {Cleo C} and Dubois, {Patrick C} and Sarah Edkins and Regina F{\"o}lster-Holst and Karin Fransen and Glass, {David N} and Heap, {Graham A R} and Sylvia Hofmann and Huizinga, {Tom W J} and Sarah Hunt and Cordelia Langford and James Lee and John Mansfield and Marrosu, {Maria Giovanna} and Mathew, {Christopher G} and Mein, {Charles A} and Joachim M{\"u}ller-Quernheim and Sarah Nutland and Suna Onengut-Gumuscu and Willem Ouwehand and Kerra Pearce and Prescott, {Natalie J} and Posthumus, {Marcel D} and Simon Potter and Giulio Rosati and Jennifer Sambrook and Jack Satsangi and Stefan Schreiber and Corina Shtir and Simmonds, {Matthew J} and Marc Sudman and Thompson, {Susan D} and Rene Toes and Gosia Trynka and Vyse, {Timothy J} and Walker, {Neil M} and Stephan Weidinger and Alexandra Zhernakova and Magdalena Zoledziewska and {Wellcome Trust Case Control Consortium} and Weersma, {Rinse K} and Gough, {Stephen C L} and Stephen Sawcer and Cisca Wijmenga and Miles Parkes and Francesco Cucca and Andre Franke and Panos Deloukas and Rich, {Stephen S} and Todd, {John A} and {van Heel}, {David A} and Craig Mowat",

year = "2011",

month = dec,

day = "27",

doi = "10.1038/ng.1037",

language = "English",

volume = "44",

pages = "3--5",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research",

number = "1",

}

Hunt, KA, Smyth, DJ, Balschun, T, Ban, M, Mistry, V, Ahmad, T, Anand, V, Barrett, JC, Bhaw-Rosun, L, Bockett, NA, Brand, OJ, Brouwer, E, Concannon, P, Cooper, JD, Dias, K-RM, van Diemen, CC, Dubois, PC, Edkins, S, Fölster-Holst, R, Fransen, K, Glass, DN, Heap, GAR, Hofmann, S, Huizinga, TWJ, Hunt, S, Langford, C, Lee, J, Mansfield, J, Marrosu, MG, Mathew, CG, Mein, CA, Müller-Quernheim, J, Nutland, S, Onengut-Gumuscu, S, Ouwehand, W, Pearce, K, Prescott, NJ, Posthumus, MD, Potter, S, Rosati, G, Sambrook, J, Satsangi, J, Schreiber, S, Shtir, C, Simmonds, MJ, Sudman, M, Thompson, SD, Toes, R, Trynka, G, Vyse, TJ, Walker, NM, Weidinger, S, Zhernakova, A, Zoledziewska, M, Wellcome Trust Case Control Consortium, Weersma, RK, Gough, SCL, Sawcer, S, Wijmenga, C, Parkes, M, Cucca, F, Franke, A, Deloukas, P, Rich, SS & Todd, JA & van Heel, DA & Mowat, C 2011, 'Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry', Nature Genetics, vol. 44, no. 1, pp. 3-5. https://doi.org/10.1038/ng.1037

TY - JOUR

T1 - Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

AU - Hunt, Karen A

AU - Smyth, Deborah J

AU - Balschun, Tobias

AU - Ban, Maria

AU - Mistry, Vanisha

AU - Ahmad, Tariq

AU - Anand, Vidya

AU - Barrett, Jeffrey C

AU - Bhaw-Rosun, Leena

AU - Bockett, Nicholas A

AU - Brand, Oliver J

AU - Brouwer, Elisabeth

AU - Concannon, Patrick

AU - Cooper, Jason D

AU - Dias, Kerith-Rae M

AU - van Diemen, Cleo C

AU - Dubois, Patrick C

AU - Edkins, Sarah

AU - Fölster-Holst, Regina

AU - Fransen, Karin

AU - Glass, David N

AU - Heap, Graham A R

AU - Hofmann, Sylvia

AU - Huizinga, Tom W J

AU - Hunt, Sarah

AU - Langford, Cordelia

AU - Lee, James

AU - Mansfield, John

AU - Marrosu, Maria Giovanna

AU - Mathew, Christopher G

AU - Mein, Charles A

AU - Müller-Quernheim, Joachim

AU - Nutland, Sarah

AU - Onengut-Gumuscu, Suna

AU - Ouwehand, Willem

AU - Pearce, Kerra

AU - Prescott, Natalie J

AU - Posthumus, Marcel D

AU - Potter, Simon

AU - Rosati, Giulio

AU - Sambrook, Jennifer

AU - Satsangi, Jack

AU - Schreiber, Stefan

AU - Shtir, Corina

AU - Simmonds, Matthew J

AU - Sudman, Marc

AU - Thompson, Susan D

AU - Toes, Rene

AU - Trynka, Gosia

AU - Vyse, Timothy J

AU - Walker, Neil M

AU - Weidinger, Stephan

AU - Zhernakova, Alexandra

AU - Zoledziewska, Magdalena

AU - Wellcome Trust Case Control Consortium

AU - Weersma, Rinse K

AU - Gough, Stephen C L

AU - Sawcer, Stephen

AU - Wijmenga, Cisca

AU - Parkes, Miles

AU - Cucca, Francesco

AU - Franke, Andre

AU - Deloukas, Panos

AU - Rich, Stephen S

AU - Todd, John A

AU - van Heel, David A

A2 - Mowat, Craig

PY - 2011/12/27

Y1 - 2011/12/27

KW - Acetylesterase/genetics

KW - Autoimmune Diseases/genetics

KW - Gene Frequency

KW - Genetic Association Studies

KW - Genetic Predisposition to Disease

KW - Genetic Variation

KW - Humans

KW - Risk Factors

KW - White People

U2 - 10.1038/ng.1037

DO - 10.1038/ng.1037

M3 - Letter

C2 - 22200769

SN - 1061-4036

VL - 44

SP - 3

EP - 5

JO - Nature Genetics

JF - Nature Genetics

IS - 1

ER -