Reduced incidence of lower-extremity amputations in people with diabetes in Scotland: A nationwide study

TY - JOUR

T1 - Reduced incidence of lower-extremity amputations in people with diabetes in Scotland

T2 - A nationwide study

AU - Kennon, Brian

AU - Leese, Graham P.

AU - Cochrane, Lynda

AU - Colhoun, Helen

AU - Wild, Sarah

AU - Stang, Duncan

AU - Sattar, Naveed

AU - Pearson, Donald

AU - Lindsay, Robert S.

AU - Morris, Andrew D.

AU - Livingstone, Shona

AU - Young, Matthew

AU - McKnight, John

AU - Cunningham, Scott

N1 - Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2012/12

Y1 - 2012/12

N2 - Objective: To establish the incidence of nontraumatic lower-extremity amputation (LEA) in people with diabetes in Scotland. Research Design and Methods: This cohort study linked national morbidity records and diabetes datasets to establish the number of people with diabetes who underwent nontraumatic major and minor LEA in Scotland from 2004 to 2008. Results: Two thousand three hundred eighty-two individuals with diabetes underwent a nontraumatic LEA between 2004 and 2008; 57.1% (n = 1,359) underwent major LEAs. The incidence of any LEA among persons with diabetes fell over the 5-year study period by 29.8% (3.04 per 1,000 in 2004 to 2.13 per 1,000 in 2008, P <0.001). Major LEA rates decreased by 40.7% from 1.87 per 1,000 in 2004 to 1.11 per 1,000 in 2008 (P <0.001). Conclusions: There has been a significant reduction in the incidence of LEA in persons with diabetes in Scotland between 2004 and 2008, principally explained by a reduction in major amputation.

AB - Objective: To establish the incidence of nontraumatic lower-extremity amputation (LEA) in people with diabetes in Scotland. Research Design and Methods: This cohort study linked national morbidity records and diabetes datasets to establish the number of people with diabetes who underwent nontraumatic major and minor LEA in Scotland from 2004 to 2008. Results: Two thousand three hundred eighty-two individuals with diabetes underwent a nontraumatic LEA between 2004 and 2008; 57.1% (n = 1,359) underwent major LEAs. The incidence of any LEA among persons with diabetes fell over the 5-year study period by 29.8% (3.04 per 1,000 in 2004 to 2.13 per 1,000 in 2008, P <0.001). Major LEA rates decreased by 40.7% from 1.87 per 1,000 in 2004 to 1.11 per 1,000 in 2008 (P <0.001). Conclusions: There has been a significant reduction in the incidence of LEA in persons with diabetes in Scotland between 2004 and 2008, principally explained by a reduction in major amputation.

U2 - 10.2337/dc12-0511

DO - 10.2337/dc12-0511

M3 - Article

C2 - 23011727

AN - SCOPUS:84869742525

SN - 0149-5992

VL - 35

SP - 2588

EP - 2590

JO - Diabetes Care

JF - Diabetes Care

IS - 12

ER -