Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

N. R. Dunn; A. Arscott; M. Thorogood; B. Faragher; L. De Caestecker; T. M. MacDonald; C. McCollum; S. Thomas; R. D. Mann

doi:10.1136/jech.54.4.293

Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

N. R. Dunn, A. Arscott, M. Thorogood, B. Faragher, L. De Caestecker, T. M. MacDonald, C. McCollum, S. Thomas, R. D. Mann

Molecular and Clinical Medicine

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Objectives: To examine the regional variation in incidence and case fatality of myocardial infarction among young women.

Design: Cross sectional survey, using population based incidence data. Setting - England, Scotland and Wales. Subjects - Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995.

Outcome measures: Incidence of myocardial infarction per 100,000 women years, with case fatality as a percentage of total cases.

Results: Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100,000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England.

Conclusions: The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.

Original language	English
Pages (from-to)	293-298
Number of pages	6
Journal	Journal of Epidemiology and Community Health
Volume	54
Issue number	4
DOIs	https://doi.org/10.1136/jech.54.4.293
Publication status	Published - 1 Apr 2000

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health

UN SDGs

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10.1136/jech.54.4.293

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title = "Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales",

abstract = "Objectives: To examine the regional variation in incidence and case fatality of myocardial infarction among young women.Design: Cross sectional survey, using population based incidence data. Setting - England, Scotland and Wales. Subjects - Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995.Outcome measures: Incidence of myocardial infarction per 100,000 women years, with case fatality as a percentage of total cases.Results: Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100,000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England.Conclusions: The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.",

author = "Dunn, {N. R.} and A. Arscott and M. Thorogood and B. Faragher and {De Caestecker}, L. and MacDonald, {T. M.} and C. McCollum and S. Thomas and Mann, {R. D.}",

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T1 - Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

AU - Dunn, N. R.

AU - Arscott, A.

AU - Thorogood, M.

AU - Faragher, B.

AU - De Caestecker, L.

AU - MacDonald, T. M.

AU - McCollum, C.

AU - Thomas, S.

AU - Mann, R. D.

PY - 2000/4/1

Y1 - 2000/4/1

N2 - Objectives: To examine the regional variation in incidence and case fatality of myocardial infarction among young women.Design: Cross sectional survey, using population based incidence data. Setting - England, Scotland and Wales. Subjects - Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995.Outcome measures: Incidence of myocardial infarction per 100,000 women years, with case fatality as a percentage of total cases.Results: Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100,000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England.Conclusions: The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.

AB - Objectives: To examine the regional variation in incidence and case fatality of myocardial infarction among young women.Design: Cross sectional survey, using population based incidence data. Setting - England, Scotland and Wales. Subjects - Subjects were women aged 16-44 with a diagnosis of myocardial infarction between 1 October 1993 and 15 October 1995.Outcome measures: Incidence of myocardial infarction per 100,000 women years, with case fatality as a percentage of total cases.Results: Incidence of myocardial infarction rose steeply from age 33 upwards, (maximum = 20.2 cases per 100,000 women years at age 44). The adjusted incidence rate for myocardial infarction was 3.7 (95% CI 3.2, 4.2) times greater in Scotland than in southern England. In contrast, case fatality was significantly lower in Scotland: 18.5% (95% CI 13.1%, 25.0%), compared with 31.0% (95% CI 25.9%, 36.0%) in southern England.Conclusions: The incidence of myocardial infarction varied widely within the United Kingdom. Case fatality variation may reflect differences in ambulance response, or in diagnostic acumen, within the regions.

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VL - 54

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JO - Journal of Epidemiology and Community Health

JF - Journal of Epidemiology and Community Health

IS - 4

ER -

Regional variation in incidence and case fatality of myocardial infarction among young women in England, Scotland and Wales

Abstract

ASJC Scopus subject areas

UN SDGs

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