Regulation of clathrin-coated vesicle formation

E. Hill; O. Olusanya; J. Van der Kaay; C. P. Downes; P. D. Andrews; J. R. Swedlow; E. Smythe

doi:10.1042/BST0290375

Regulation of clathrin-coated vesicle formation

E. Hill, O. Olusanya, J. Van der Kaay, C. P. Downes, P. D. Andrews, J. R. Swedlow, E. Smythe (Lead / Corresponding author)

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Abstract

The formation of clathrin-coated pits at the plasma membrane requires the concerted action of many different molecules. The real challenge lies in determining the hierarchy of these interactions. We are using assays in both intact and permeabilized cells to dissect the temporal requirements for clathrin-coated vesicle formation, and also to examine the role of phosphorylation of the coat proteins.

Original language	English
Pages (from-to)	375-377
Number of pages	3
Journal	Biochemical Society Transactions
Volume	29
Issue number	4
DOIs	https://doi.org/10.1042/BST0290375
Publication status	Published - 1 Aug 2001

Keywords

μ2
Dynamin
Endophilin
Phosphorylation
Synaptojanin

ASJC Scopus subject areas

Biochemistry

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10.1042/BST0290375

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abstract = "The formation of clathrin-coated pits at the plasma membrane requires the concerted action of many different molecules. The real challenge lies in determining the hierarchy of these interactions. We are using assays in both intact and permeabilized cells to dissect the temporal requirements for clathrin-coated vesicle formation, and also to examine the role of phosphorylation of the coat proteins.",

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AU - Hill, E.

AU - Olusanya, O.

AU - Van der Kaay, J.

AU - Downes, C. P.

AU - Andrews, P. D.

AU - Swedlow, J. R.

AU - Smythe, E.

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AB - The formation of clathrin-coated pits at the plasma membrane requires the concerted action of many different molecules. The real challenge lies in determining the hierarchy of these interactions. We are using assays in both intact and permeabilized cells to dissect the temporal requirements for clathrin-coated vesicle formation, and also to examine the role of phosphorylation of the coat proteins.

KW - μ2

KW - Dynamin

KW - Endophilin

KW - Phosphorylation

KW - Synaptojanin

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JF - Biochemical Society Transactions

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ER -

Regulation of clathrin-coated vesicle formation

Abstract

Keywords

ASJC Scopus subject areas

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