Regulation of cytosolic enzymes in primary metabolism by reversible protein phosphorylation

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    Recent discoveries have revealed that cytosolic enzymes of sugar, amino acid, and isoprenoid synthesis, sucrose breakdown and the plasma membrane H+-ATPase are regulated by reversible protein (serine/threonine) phosphorylation. In some cases, phosphorylation creates a phosphopeptide motif that is recognized by and binds to 14-3-3 proteins, and 14-3-3 binding changes the activity of the enzyme or ion pump. Intriguing new clues hint at how these cytosolic regulatory networks might link to signalling pathways triggered by hormones, nutrients, stresses, circadian rhythms, and other factors that regulate the growth and development of the whole plant.

    Original languageEnglish
    Pages (from-to)224-229
    Number of pages6
    JournalCurrent Opinion in Plant Biology
    Issue number3
    Publication statusPublished - 1998

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