Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

Keyphrases

• Stress Response 100%
• Protein Complex 100%
• Associated Proteins 100%
• NFE2L2 100%
• Regulatory Flexibility 100%
• Inducer 16%
• Single Molecule 8%
• Cellular Level 8%
• Transcription Factor 8%
• Ubiquitination 8%
• Recombinant Protein 8%
• Ubiquitin Ligase 8%
• Electrophile 8%
• Transcriptional Response 8%
• Adaptor Protein 8%
• Cytoprotective Genes 8%
• Master Regulator 8%
• Multiphoton Fluorescence 8%
• Transfer Based 8%
• Förster Resonance Energy Transfer 8%
• Fluorescence Lifetime Imaging 8%
• Regulation Mode 8%
• Single Living Cell 8%
• Closed Conformation 8%
• Multiple Modes 8%
• Recombinant Population 8%
• Response to Environmental Change 8%
• Cullin3 8%
• Attachment Model 8%
• Regeneration Model 8%
• Dynamism 8%

Neuroscience

• Protein Complexes 100%
• Synapsin I 100%
• Prothrombin 100%
• Ubiquitination 8%
• Adaptor Protein 8%
• Oxidizing Agent 8%
• Transcription Factor NF E2 P45 Subunit 8%
• Recombinant Protein 8%
• Energy Transfer 8%
• Ubiquitin Protein Ligase 8%

Biochemistry, Genetics and Molecular Biology

• Protein Complexes 100%
• Synapsin I 100%
• Conformation 20%
• Energy Transfer 10%
• Cell Level 10%
• Ubiquitination 10%
• Recombinant Protein 10%
• Transcription Factor NF E2 P45 Subunit 10%
• Ubiquitin Ligase 10%
• Fluorescence-Lifetime Imaging Microscopy 10%