Relationships between impulse oscillometry, spirometry and dyspnoea in COPD

W. J. Anderson, B. J. Lipworth

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    25 Citations (Scopus)


    Background: Severity of chronic obstructive pulmonary disease (COPD) is based either on symptoms/disability or lung function, which have no discernible correlation. We hypothesised that impulse oscillometry (IOS), a non-effortdependent measure of central and peripheral airway mechanics, could correlate to dyspnoea in COPD. Methods: We analysed screening data from 57 COPD patients who had spirometry, IOS and Medical Research Council dyspnoea score (MRC) measurements. We searched for predictors or correlations of MRC from IOS, spirometry and demographics. Results: MRC had no significant predictors or correlations from IOS, spirometry or demographics (possibly excepting smoking history, p=0.05). IOS correlated significantly with spirometry: FEV1 and FEF25-75 vs. R5-R20 (peripheral airway resistance), r=-0.499, p
    Original languageEnglish
    Pages (from-to)111-115
    Number of pages5
    JournalJournal of the Royal College of Physicians of Edinburgh
    Issue number2
    Publication statusPublished - 2012


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